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GTR Home > Tests > Genomic Unity Motor Neuron Disorders Analysis (includes AR, C9ORF72 STR analysis)

Performance Characteristics



  • Interpretation performed in-house
  • Report generated in-house
  • Specimen preparation performed at an outside lab
  • Wet lab work performed at an outside lab
  • Specimen preparation and clinical grade sequencing is performed by outside CLIA labs. All data processing, analysis, interpretation and report generation is performed in-house.

Analytical Validity


The Genomic Unity® Motor Neuron Disorders Analysis is designed to identify genetic variants that correlate with motor neuron disorders. This analysis includes sequence analysis (single nucleotide variants, deletions/insertions, and characterized intronic variants), copy number variants, duplications/deletions, mobile element insertions, and inversions in a panel of 116 genes, and short tandem repeat expansions in AR and C9ORF72. The sensitivity, specificity and positive predictive value of the assay is greater than 0.99 for single nucleotide variants and small insertions and deletions less than 50 base pairs. The analytical sensitivity for copy number variants reported in this assay is greater than 0.80 for variants over 300 base pairs, while the clinical sensitivity for copy number variants of any size is over 0.96. The clinical sensitivity of this test is over 0.99 for pathogenic short tandem repeats.


Not provided

Proficiency Testing (PT)

Is proficiency testing performed for this test? Help
Method used for proficiency testingHelp

FDA Regulatory Clearances of the Test


Not provided

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