Overview
Test order codeHelpLaboratory's order or catalog code for the test (used in the order requisition form).: 81415, 81416
NextStepDx PLUS (NSDX)
This is a clinical test intended for HelpPurposes or indications for the test. Lab-provided.: Diagnosis, Prognostic, Recurrence, Therapeutic management
Click Indication tab for more information.
To order, please call 801-931-6200 to discuss the ordering process or order buccal sample collection kits. The test requisition form can be found on www.lineagen.com/how-to-order
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: http://www.lineagen.com
Specimen source
Buccal swab
Isolated DNA
Peripheral (whole) blood
- Molecular Genetics
- CSequence analysis of the entire coding region
- Next-Generation (NGS)/Massively parallel sequencing (MPS)
- Illumina HiSeq™2000 system
- Agilent SureSelect Human All Exon V6
Lower cost than traditional diagnostic pathways
Citations- A clinical utility study of exome sequencing versus conventional genetic testing in pediatric neurology. - PubMed ID:
28333917
- Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions. - PubMed ID:
28759686
- Integrating exome sequencing into a diagnostic pathway for epileptic encephalopathy: Evidence of clinical utility and cost effectiveness. - PubMed ID:
29314763
Establish or confirm diagnosis
Citations- Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions. - PubMed ID:
28759686
Avoidance of invasive testing
Citations- Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions. - PubMed ID:
28759686
Not provided
- Genetic counseling, comments
- Insurance pre-authorization/appeals assistance
IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.
