NextStepDx PLUS
- GTR Test IDHelpEach Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version number is assigned.: GTR000576359.2
- Last updated: 2022-04-13
- Test version history
Clinical testHelpIn the U.S., clinical tests must be performed under CLIA certification. When a lab uses the same methods for a test in both clinical and research settings, the test appears as two separate GTR records. for Epilepsy
Offered by Bionano Laboratories
Overview
Test name
HelpThe name the laboratory assigns the test. Used as the default title of the page specific to the test.NextStepDx PLUS (NSDX)
This is a clinical test intended for HelpPurposes or indications for the test. Lab-provided.: Diagnosis, Prognostic, Recurrence, Therapeutic management
Click Indication tab for more information.
To order, please call 801-931-6200 to discuss the ordering process or order buccal sample collection kits. The test requisition form can be found on www.lineagen.com/how-to-order
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: http://www.lineagen.com
Specimen source
Methodology
HelpThe assay's major method category (biochemical, cytogenetic or molecular genetics); method category (i.e. enzyme assay, chromosome breakage studies, targeted mutation analysis); methodology (i.e. the name of the method used) and instruments used when performing this test.- Molecular Genetics
- CSequence analysis of the entire coding region
- Next-Generation (NGS)/Massively parallel sequencing (MPS)
- Illumina HiSeq™2000 system
- Agilent SureSelect Human All Exon V6
Lower cost than traditional diagnostic pathways
- A clinical utility study of exome sequencing versus conventional genetic testing in pediatric neurology. - PubMed ID: 28333917
- Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions. - PubMed ID: 28759686
- Integrating exome sequencing into a diagnostic pathway for epileptic encephalopathy: Evidence of clinical utility and cost effectiveness. - PubMed ID: 29314763
Establish or confirm diagnosis
- Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions. - PubMed ID: 28759686
Avoidance of invasive testing
- Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions. - PubMed ID: 28759686
Clinical validity
HelpHow consistently and accurately the test detects or predicts the intermediate or final outcomes of interest. Lab-provided.Not provided
Test services
HelpLaboratory's order or catalog code for the test (used in the order requisition form).- Genetic counseling, commentsAvailable via telephone
- Insurance pre-authorization/appeals assistance
IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.