Classic view of this page
UCSF500 Cancer Gene Panel
Clinical Genetic Test
Help
offered by
Clinical Cancer Genomics Laboratory
View lab's test page
LinkOut
GTR Test Accession: Help GTR000591895.1
CANCERDYSMORPHOLOGYRESPIRATORY DISEASE ... View more
Last updated in GTR: 2020-10-06
View version history
Last annual review date for the lab: 2022-10-17 Past due LinkOut
At a Glance
Test purpose: Help
Diagnosis; Mutation Confirmation; Prognostic; ...
Conditions (2): Help
Melanoma; Neoplasm of lung
Genes (2): Help
BRAF (7q34), EGFR (7p11.2)
Methods (1): Help
Molecular Genetics - Sequence analysis of the entire coding region: Next-Generation (NGS)/Massively parallel sequencing (MPS)
Target population: Help
Patients presenting with solid tumors or hematopoietic malignancies.
Clinical validity: Help
Not provided
Clinical utility: Help
Not provided
Ordering Information
Offered by: Help
Clinical Cancer Genomics Laboratory
View lab's website
View lab's test page
Test short name: Help
U500
Specimen Source: Help
Who can order: Help
  • Health Care Provider
  • Nurse Practitioner
Test Order Code: Help
UCSF500
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
Test service: Help
Clinical Testing/Confirmation of Mutations Identified Previously
Test development: Help
Test developed by laboratory (no manufacturer test name)
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
How to Order, Lab contact for this test, Test strategy
Conditions Help
Total conditions: 2
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 2
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument
Sequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Illumina NovaSeq 6000 system
Clinical Information
Test purpose: Help
Diagnosis; Mutation Confirmation; Prognostic; Recurrence; Therapeutic management
Target population: Help
Patients presenting with solid tumors or hematopoietic malignancies.
Recommended fields not provided:
Clinical validity, Clinical utility, What is the protocol for interpreting a variation as a VUS?, Are family members with defined clinical status recruited to assess significance of VUS without charge?, Will the lab re-contact the ordering physician if variant interpretation changes?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
The UCSF500 assay was initially validated in 2015, and revalidated with a change to our capture probes in 2016 and 2020. During these rounds of validation, specimens with external testing results from CLIA/CAP certified labs were used to establish accuracy. The external reference method included commercial send-out cancer gene panel … View more
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Alternative Assessment
Recommended fields not provided:
Test Confirmation, Assay limitations, Description of internal test validation method, Citations for Analytical validity, PT Provider, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Not provided
Additional Information
Practice guidelines:
Consumer resources:

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.