U.S. flag

An official website of the United States government

GTR Home > Tests > Chromosome Analysis (High Resolution), Peripheral Blood

Performance Characteristics



  • Entire test performed in-house

Analytical Validity


Minimal band resolution is 550 bands. This test analyzes 20 metaphase cells to identify numerical and structural chromosome abnormalities and can detect mosaicism down to 20% of cells at 95th confidence interval. Mosaicism study (50-cell extended cell count evaluation) available, which can detect mosaicism down to 6% of cells at 95th confidence interval.


Not provided

Proficiency Testing (PT)

Is proficiency testing performed for this test? Help
Method used for proficiency testingHelp
Formal PT program
PT ProviderHelp
College of American Pathologists, CAP

FDA Regulatory Clearances of the Test

FDA Category Designation
Not Applicable

Practice guidelines

  • NSGC, 2021
    National Society of Genetic Counselors Position Statement: Prenatal Cell-Free DNA Screening

Consumer resources

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.