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GTR Home > Tests > CYP2D6 single gene analysis


Test order codeHelp: SGAD008

Test name


CYP2D6 single gene analysis

Purpose of the test


This is a clinical test intended for Help: Drug Response



Click Indication tab for more information.

How to order


Not provided


Molecular Genetics
TTargeted variant analysis
SNP Detection

Summary of what is tested

Click Methodology tab for more information.

Clinical utility


Not provided

Clinical validity


Not provided

Practice guidelines

  • NCCN, 2022
    Breast Cancer, NCCN Guidelines Version 4.2022
  • ASCO, 2019
    Adjuvant Endocrine Therapy for Women With Hormone Receptor-Positive Breast Cancer: ASCO Clinical Practice Guideline Focused Update
  • NCCN, 2014
    National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology. Breast Cancer (See 2022 Update)
  • DailyMed Drug Label, 2013
    DailyMed Drug Label, tamoxifen, 2013
  • ACMG, 2012
    Laboratory testing of CYP2D6 alleles in relation to tamoxifen therapy.
  • DPWG, 2011
    Pharmacogenetics: from bench to byte--an update of guidelines.
  • ASCO, 2010
    American Society of Clinical Oncology Clinical Practice Guideline Update on Adjuvant Endocrine Therapy for Women With Hormone Receptor-Positive Breast Cancer (See 2019 Update)
  • NACB, 2010
    National Academy of Clinical Biochemistry, Clinical practice considerations. In: Laboratory medicine practice guidelines: guidelines and recommendations for laboratory analysis and application of pharmacogenetics to clinical practice, 2010

Consumer resources

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.