Overview
Test order codeHelpLaboratory's order or catalog code for the test (used in the order requisition form).: NEPHP
Comprehensive Nephrology Gene Panel (NEPHP)
This is a clinical test intended for HelpPurposes or indications for the test. Lab-provided.: Diagnosis
Click Indication tab for more information.
https://www.mayocliniclabs.com/test-catalog/Overview/618086#Specimen
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: https://www.mayocliniclabs.com/order-tests/index.html
Specimen source
Peripheral (whole) blood
- Molecular Genetics
- DDeletion/duplication analysis
- Next-Generation (NGS)/Massively parallel sequencing (MPS)
- CSequence analysis of the entire coding region
- Next-Generation (NGS)/Massively parallel sequencing (MPS)
Establish or confirm diagnosis
Citations- Bernabeu-Herrero ME, Jimenez-Alcazar M, Anter J, et al. Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome. Mol Immunol. 2015 Oct;67(2 Pt B):276-286. doi: 10.1016/j.molimm.2015.06.021
- Downie ML, Lopez Garcia SC, Kleta R, Bockenhauer D: Inherited tubulopathies of the kidney: Insights from genetics. Clin J Am Soc Nephrol. 2021 Apr 7;16(4):620-630. doi: 10.2215/CJN.14481119
- Lanktree MB, Haghighi A, di Bari I, Song X, Pei Y: Insights into autosomal dominant polycystic kidney disease from genetic studies. Clin J Am Soc Nephrol. 2021 May 8;16(5):790-799. doi: 10.2215/CJN.02320220
- Lemaire M, Noone D, Lapeyraque AL, Licht C, Fremeaux-Bacchi V: Inherited kidney complement diseases. Clin J Am Soc Nephrol. 2021 Jun;16(6):942-956. doi:10.2215/CJN.11830720
- Li AS, Ingham JF, Lennon R: Genetic disorders of the glomerular filtration barrier. Clin J Am Soc Nephrol. 2020 Dec 7;15(12):1818-1828. doi: 10.2215/CJN.11440919
- Nishimura J, Yamamoto M, Hayashi S, et al. Genetic variants in C5 and poor response to eculizumab. N Engl J Med. 2014 Feb13;370(7):632-639. doi: 10.1056/NEJMoa1311084
- Parsa A, Kao WH, Xie D, et al: APOL1 risk variants, race, and progression of chronic kidney disease. N Engl J Med. 2013 Dec 5;369(23):2183-2196. doi: 10.1056/NEJMoa1310345
- Quinlan C, Rheault MN: Genetic basis of type IV collagen disorders of the kidney. Clin J Am Soc Nephrol. 2021 Jul;16(7) 1101-1109. doi: 10.2215/CJN.19171220
Not provided
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