U.S. flag

An official website of the United States government

GTR Home > Tests > Solid Tumor Panel

Solid Tumor Panel

  • GTR Test IDHelp: GTR000601603.1
  • Last updated: 2022-11-07
  • Test version history

Clinical testHelp for Melanoma-pancreatic cancer syndrome
Offered by Centogene US, LLC - The Rare Disease Company

Indication

This is a clinical test intended for Help: Diagnosis

Clinical summary

Help

Imported from OMIM

Melanoma-pancreatic cancer syndrome is an inherited cancer predisposition syndrome in which mutation carriers have an increased risk of developing malignant melanoma and/or pancreatic cancer. Mutation carriers within families may develop either or both types of cancer (summary by Harinck et al., 2012). For background and phenotypic information on malignant melanoma and pancreatic cancer, see 155600 and 260350, respectively.

Clinical features

Help

Imported from Human Phenotype Ontology (HPO)

  • Squamous cell carcinoma
  • Melanoma
  • Oropharyngeal squamous cell carcinoma
  • Pancreatic adenocarcinoma
  • Sarcoma
  • Pancreatic squamous cell carcinoma
Show all

Inheritance pattern

Help

Autosomal dominant inheritance

Conditions tested

Target population

Help

Not provided

Clinical validity

Help

This panel should be performed in all individuals suspected of having an overlapping clinical phenotype. Confirmation of a clinical diagnosis through genetic testing can allow for genetic counseling and may direct medical management. Genetic counseling can provide a patient and/or family with the natural history of the condition, identify at-risk family members, provide reproductive risks as well as preconception/prenatal options, and allow for appropriate referral for patient support and/or resources.

Citations

Not provided

Clinical utility

Help

Not provided

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.