Classic view of this page
GLOBALpgx
Clinical Genetic Test
Help
offered by
Eugenomic S.L.
View lab's test page
LinkOut
GTR Test Accession: Help GTR000604090.3
Last updated in GTR: 2023-12-27
View version history
Last annual review date for the lab: 2023-12-27 LinkOut
At a Glance
Test purpose: Help
Therapeutic management; Drug Response
Conditions (1): Help
Drug metabolism or response
Genes (21): Help
ABCB1 (7q21.12), ABCG2 (4q22.1), BCHE (3q26.1), CACNA1A (19p13.13), CYP1A2 (15q24.1), ...
Methods (1): Help
Molecular Genetics - Targeted variant analysis: Microarray
Target population: Help
Polymedicated, starting new medication, history of adverse drug reactions.
Clinical validity: Help
Not provided
Clinical utility: Help
Not provided
Ordering Information
Offered by: Help
Eugenomic S.L.
View lab's website
View lab's test page
Test short name: Help
GLOBALpgx
Manufacturer's name: Help
Eugenomic
Specimen Source: Help
Who can order: Help
  • Genetic Counselor
  • Health Care Provider
  • Public Health Mandate
  • Nurse Practitioner
  • Physician Assistant
  • Licensed Dentist
  • Licensed Physician
  • Registered Nurse
Test Order Code: Help
GLOBALpgx
View other test codes
Lab contact: Help
Marc Cendrós, Genetic Counselor
info@eugenomic.com
0034932922963
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
Post-test email/phone consultation regarding genetic test results and interpretation is provided to patients/families.
Pre-test email/phone consultation regarding genetic test results and interpretation is provided to patients/families.
How to Order: Help
Go to the URL provided, press the request button. Follow the instructions and do not forget to include the doctor name or clinic.
Sample type: EDTA blood or saliva.
Turn around time: 2 weeks from reception of the sample.
Order URL
Test service: Help
Genetic counseling
    OrderCode: 45645
Test development: Help
Test developed by laboratory (no manufacturer test name)
Informed consent required: Help
Yes
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Test strategy
Conditions Help
Total conditions: 1
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 21
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument *
Targeted variant analysis
Microarray
* Instrument: Not provided
Clinical Information
Test purpose: Help
Therapeutic management; Drug Response
Target population: Help
Polymedicated, starting new medication, history of adverse drug reactions.
View citations (12)
  • PharmGKB: the Pharmacogenetics Knowledge Base. Hewett M, et al. Nucleic Acids Res. 2002;30(1):163-5. doi:10.1093/nar/30.1.163. PMID: 11752281.
  • Pharmacogenetics research network and knowledge base: 1st annual scientific meeting. Davis A, et al. Pharmacogenomics. 2001;2(3):285-9. doi:10.1517/14622416.2.3.285. PMID: 11939133.
  • Swen JJ, Wilting I, de Goede AL, Grandia L, Mulder H, Touw DJ, de Boer A, Conemans JM, Egberts TC, Klungel OH, Koopmans R, van der Weide J, Wilffert B, Guchelaar HJ, Deneer VH. Pharmacogenetics: from bench to byte. Clin Pharmacol Ther. 2008;83(5):781-7. doi:10.1038/sj.clpt.6100507. Epub 2008 Feb 06. PMID: 18253145.
  • Relling MV, Klein TE. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther. 2011;89(3):464-7. doi:10.1038/clpt.2010.279. Epub 2011 Jan 26. PMID: 21270786.
  • Swen JJ, Nijenhuis M, de Boer A, Grandia L, Maitland-van der Zee AH, Mulder H, Rongen GA, van Schaik RH, Schalekamp T, Touw DJ, van der Weide J, Wilffert B, Deneer VH, Guchelaar HJ. Pharmacogenetics: from bench to byte--an update of guidelines. Clin Pharmacol Ther. 2011;89(5):662-73. doi:10.1038/clpt.2011.34. Epub 2011 Mar 16. PMID: 21412232.
  • Emergency hospitalizations for adverse drug events in older Americans. Budnitz DS, et al. N Engl J Med. 2011;365(21):2002-12. doi:10.1056/NEJMsa1103053. PMID: 22111719.
  • Pharmacogenomics knowledge for personalized medicine. Whirl-Carrillo M, et al. Clin Pharmacol Ther. 2012;92(4):414-7. doi:10.1038/clpt.2012.96. PMID: 22992668.
  • Caudle KE, Dunnenberger HM, Freimuth RR, Peterson JF, Burlison JD, Whirl-Carrillo M, Scott SA, Rehm HL, Williams MS, Klein TE, Relling MV, Hoffman JM. Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC). Genet Med. 2017;19(2):215-223. doi:10.1038/gim.2016.87. Epub 2016 Jul 21. PMID: 27441996.
  • Gaedigk A, Ingelman-Sundberg M, Miller NA, Leeder JS, Whirl-Carrillo M, Klein TE, . The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database. Clin Pharmacol Ther. 2018;103(3):399-401. doi:10.1002/cpt.910. Epub 2017 Nov 14. PMID: 29134625.
  • Sabater A, Ciudad CJ, Cendros M, Dobrokhotov D, Sabater-Tobella J. g-Nomic: a new pharmacogenetics interpretation software. Pharmgenomics Pers Med. 2019;12:75-85. doi:10.2147/PGPM.S203585. Epub 2019 May 29. PMID: 31239753.
  • • Food and Drug Administration. Drug Safety Labeling Changes [online]. . [Monthly access]
  • • Sabater, J., Sabater, G. (2010). Medicina Personalizada Posgenómica: Conceptos Prácticos para Clínicos. Elsevier. ISBN: 978-84-458-2025-4. doi: 10.1016/B978-84-458-2025-4.X0001-0
Recommended fields not provided:
Clinical validity, Clinical utility, What is the protocol for interpreting a variation as a VUS?, Are family members with defined clinical status recruited to assess significance of VUS without charge?, Will the lab re-contact the ordering physician if variant interpretation changes?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Availability: Help
Tests performed
Wet lab work performed at an outside lab
Report generated in-house
Interpretation performed in-house
Specimen preparation performed both in-house and at an outside lab

Test performance comments
DNA extraction and genotyping is performed at a collaboration lab.
Analytical Validity: Help
Quality control by visual inspection of fluorescence plots and confirmation by Sanger sequencing when any unclear results. Accuracy and analytical sensitivity for targeted variant(s) (SNVs and INDELs): (>99%).
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
No
Recommended fields not provided:
Test Confirmation, Assay limitations, Description of internal test validation method, Citations for Analytical validity, PT Provider, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Not provided
Additional Information
Consumer resources:

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.