Prenatal aneuploidy interphase FISH
GTR Test Accession: Help GTR000613131.1
CAP
Last updated in GTR: 2024-01-09
Last annual review date for the lab: 2024-01-08 LinkOut
At a Glance
Diagnosis; Risk Assessment
Down syndrome (Trisomy 21) Patau syndrome (Trisomy 13) Edwards syndrome (Trisomy 18) Klinefelter syndrome (47,XXY) Turner syndrome (45, XO), and aneuploidies corresponding to the 46 chromosome screening
Xcen(DXZ1), Ycen(DYZ3), 18cen(D18Z1), 13q14(RB1), 21q22.12(RCAN1)
Cytogenetics - FISH-interphase: Fluorescence in situ hybridization (FISH)
Rapid detection of aneuploidy involving chromosomes 13, 18, 21, X …
Not provided
Not provided
Ordering Information
Offered by: Help
Clinical Cytogenetics Laboratory
View lab's website
View lab's test page
Specimen Source: Help
Who can order: Help
  • Health Care Provider
Test Order Code: Help
See Labcorp test menu for code options
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Health care providers should submit an order (electronically or hard copy requisition) under their specific LabCorp account number.
Order URL
Test service: Help
Custom Deletion/Duplication Testing
    Comment: commercially available FISH probes
Informed consent required: Help
Decline to answer
Test strategy: Help
Various reflex test code options involving Interphase aneuploidy FISH are available. See Labcorp test menu for more specific information.
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Conditions Help
Total conditions: 1
Condition/Phenotype Identifier
Test Targets
Chromosomal regions/Mitochondria Help
Total chromosomal regions/mitochondria: 1
Chromosomal region/Mitochondrion Associated condition
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument *
FISH-interphase
Fluorescence in situ hybridization (FISH)
* Instrument: Not provided
Clinical Information
Test purpose: Help
Diagnosis; Risk Assessment
Target population: Help
Rapid detection of aneuploidy involving chromosomes 13, 18, 21, X and Y in prenatal samples. Assay offered in conjunction with other prenatal cytogenetic testing.
Recommended fields not provided:
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
FISH validation studies have demonstrated greater than 99% analytical sensitivity for detecting aneuploidy of chromosomes 13, 18, 21, X and Y.
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Formal PT program

PT Provider: Help
College of American Pathologists, CAP
Recommended fields not provided:
Regulatory Approval
FDA Review: Help
Not provided
Additional Information

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