Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Spike Antibody, Semi-Quantitative, Serum
- GTR Test IDHelpEach Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version number is assigned.: GTR000592502.2
- Last updated: 2021-07-14
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- Test version history
Clinical microbial testHelpIn the U.S., clinical tests must be performed under CLIA certification. When a lab uses the same methods for a test in both clinical and research settings, the test appears as two separate GTR records. for COVID-19
Offered by Clinical Microbiology
Overview
Test name
HelpThe name the laboratory assigns the test. Used as the default title of the page specific to the test.Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Spike Antibody, Semi-Quantitative, Serum (SARS-CoV-2 Spike Ab, Semi-Quant, S)
This is a clinical microbial test intended for HelpPurposes or indications for the test. Lab-provided.: Screening
Click Indication tab for more information.
CPT Code 86769. Contact Customer Service (https://www.mayocliniclabs.com/customer-service/contacts.html)
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: https://www.mayocliniclabs.com/order-tests/account-setup.html
Specimen source
Sample requirements
For details on sample collection, see https://www.mayocliniclabs.com/test-catalog/Specimen/614035Turnaround time
Same day Monday through SaturdayMethodology
HelpThe assay's major method category (biochemical, cytogenetic or molecular genetics); method category (i.e. enzyme assay, chromosome breakage studies, targeted mutation analysis); methodology (i.e. the name of the method used) and instruments used when performing this test.- Serology
- OAntibody assay
- Electrochemiluminescence Immunoassay (ECLIA)
- cobas Elecsys Anti-SARS-CoV-2 S Antibody (Roche Diagnostics)
Not provided
Clinical validity
HelpHow consistently and accurately the test detects or predicts the intermediate or final outcomes of interest. Lab-provided.Not provided
Comments about the test interpretation (e.g. clinical implication of test results)
This assay provides qualitative and semi-quantitative results for the presence of antibodies to the receptor binding domain (RBD) on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein. Both vaccine and active infection can stimulate antibodies against this domain. Negative: No antibodies to SARS-CoV-2 spike glycoprotein detected. Negative results may occur in serum collected too soon following infection or vaccination, in immunosuppressed patients or in patients with mild or asymptomatic infection. This test does not rule out active or recent coronavirus disease 2019 (COVID-19) infection or vaccination. Follow up testing with a molecular test for SARS-CoV-2 is recommended in symptomatic patients. Positive: Antibodies to the SARS-CoV-2 spike glycoprotein detected. These results suggest recent or prior SARS-CoV-2 infection or vaccination. No minimum antibody level or threshold has been established to indicate long-term protective immunity against re-infection. Correlation with epidemiologic risk factors and other clinical and laboratory findings is recommended. Serologic results should not be used to diagnose recent SARS-CoV-2 infection. False-positive results for IgG antibodies may occur due to cross-reactivity from pre-existing antibodies or other possible causes.IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.