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HomoloGene:121718. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PRKACB,  H.sapiens
protein kinase, cAMP-dependent, catalytic, beta
NP_891993.1
398 aa
PRKACB,  P.troglodytes
protein kinase, cAMP-dependent, catalytic, beta
XP_001137476.1
398 aa
PRKACB,  M.mulatta
protein kinase, cAMP-dependent, catalytic, beta
XP_001105747.2
398 aa
LOC479975,  C.lupus
cAMP-dependent protein kinase catalytic subunit beta-like
XP_537099.1
397 aa
PRKACB,  B.taurus
protein kinase, cAMP-dependent, catalytic, beta
NP_777010.1
351 aa
Prkacb,  M.musculus
protein kinase, cAMP dependent, catalytic, beta
NP_001157672.1
398 aa
Prkacb,  R.norvegicus
protein kinase, cAMP dependent, catalytic, beta
NP_001071113.1
351 aa
PRKACB,  G.gallus
protein kinase, cAMP-dependent, catalytic, beta
XP_422379.1
398 aa
prkacb,  X.tropicalis
protein kinase, cAMP-dependent, catalytic, beta
NP_001164667.1
351 aa
prkacbb,  D.rerio
protein kinase, cAMP-dependent, catalytic, beta b
NP_001030148.1
351 aa
prkacb,  D.rerio
protein kinase, cAMP-dependent, catalytic, beta
XP_003197858.1
351 aa
Pka-C1,  D.melanogaster
cAMP-dependent protein kinase 1
NP_995672.1
353 aa
AgaP_AGAP001384,  A.gambiae
AgaP_AGAP001384
XP_321752.4
353 aa
kin-1,  C.elegans
kin-1
NP_493605.1
359 aa
TPK1,  S.cerevisiae
TPK1
NP_012371.2
397 aa
MGG_06368,  M.oryzae
MGG_06368
XP_003717206.1
539 aa
NCU06240,  N.crassa
NCU06240
XP_963091.1
536 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

D.melanogaster
Encodes one of the isoforms of the catalytic subunit form of Pka. Drosophila cAMP-dependent protein kinase has been purified from the bodies of adult flies; the enzyme is made up of catalytic and regulatory subunits (Foster, Guttman, Hall and Rosen, 1984). The catalytic subunit has a molecular weight of 40,000 and the regulatory subunit a molecular weight of 52,000 or 58,000 (based on electrophoretic mobilities in sodium dodecyl sulfate-polyacrylamide gels)



Publications
Articles associated with genes and sequences of this homology group.

Protein kinase A inhibits a consolidated form of memory in Drosophila.
Horiuchi J, et al. Proc Natl Acad Sci U S A 105, 20976-81 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkacb includes H.sapiens PRKACB and R.norvegicus Prkacb.

 

 

 

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