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HomoloGene:128036. Gene conserved in Catarrhini Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GH1,  H.sapiens
growth hormone 1
NP_000506.2
217 aa
GH1,  P.troglodytes
growth hormone 1
NP_001184093.1
217 aa
GH1,  M.mulatta
growth hormone 1
NP_001036203.1
217 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Growth hormone deficiency.
Growth hormone deficiency, isolated, type II.
Growth hormone deficiency, isolated, type IA.
Growth hormone deficiency, isolated, type IB.
Kowarski syndrome.
Short stature, familial.



Publications
Articles associated with genes and sequences of this homology group.

Determinants of GH resistance in malnutrition.
Fazeli PK & Klibanski A. J Endocrinol 220, R57-65 (2014).
Isolated growth hormone deficiency type 2: from gene to therapy.
Miletta MC, et al. Endocr Dev 23, 109-20 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
growth_hormone_like (cl07831)
  Somatotropin/prolactin hormone family.

 

 

 

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