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HomoloGene:128347. Gene conserved in Catarrhini Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

CSH1,  H.sapiens
chorionic somatomammotropin hormone 1 (placental lactogen)
217 aa
CSH2,  H.sapiens
chorionic somatomammotropin hormone 2
217 aa
PL-D,  P.troglodytes
placental lactogen PL-D
217 aa
LOC735307,  M.mulatta
chorionic somatomammotropin-1
217 aa
CSH2,  M.mulatta
chorionic somatomammotropin hormone 2
217 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Placental lactogen deficiency.

Articles associated with genes and sequences of this homology group.

Crystal structure and site 1 binding energetics of human placental lactogen.
Walsh ST & Kossiakoff AA. J Mol Biol 358, 773-84 (2006).
Short stature caused by a biologically inactive mutant growth hormone (GH-C53S).
Besson A, et al. J Clin Endocrinol Metab 90, 2493-9 (2005).
Placental mRNA in maternal plasma: prospects for fetal screening.
Ferguson-Smith MA. Proc Natl Acad Sci U S A 100, 4360-2 (2003).
mRNA of placental origin is readily detectable in maternal plasma.
Ng EK, et al. Proc Natl Acad Sci U S A 100, 4748-53 (2003).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
growth_hormone_like (cl07831)
  Somatotropin/prolactin hormone family.




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