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HomoloGene:129823. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CLDN22,  H.sapiens
claudin 22
NP_001104789.1
220 aa
CLDN22,  P.troglodytes
claudin 22
XP_001160888.1
220 aa
CLDN22,  M.mulatta
claudin 22
XP_001092698.1
219 aa
CLDN22,  C.lupus
claudin 22
XP_005630069.1
221 aa
CLDN22,  B.taurus
claudin 22
XP_002698716.2
221 aa
CLDN24,  B.taurus
claudin 24
XP_002698717.1
220 aa
Cldn22,  M.musculus
claudin 22
NP_083659.1
220 aa
Cldn22,  R.norvegicus
claudin 22
NP_001103613.1
220 aa
Cldn24,  R.norvegicus
claudin 24
NP_001103614.1
220 aa
LOC100858888,  G.gallus
claudin-22-like
XP_004941127.1
217 aa
cldn22,  X.tropicalis
claudin 22
XP_002934304.1
220 aa
si:dkey-98f17.3,  D.rerio
si:dkey-98f17.3
NP_001116178.1
220 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Biology of claudins.
Angelow S, et al. Am J Physiol Renal Physiol 295, F867-76 (2008).
Tight junction proteins.
González-Mariscal L, et al. Prog Biophys Mol Biol 81, 1-44 (2003).
Claudin-based barrier in simple and stratified cellular sheets.
Tsukita S & Furuse M. Curr Opin Cell Biol 14, 531-6 (2002).
Multifunctional strands in tight junctions.
Tsukita S, et al. Nat Rev Mol Cell Biol 2, 285-93 (2001).
Tight junctions of the blood-brain barrier.
Kniesel U & Wolburg H. Cell Mol Neurobiol 20, 57-76 (2000).
The claudins.
Lal-Nag M & Morin PJ. Genome Biol 10, 235 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PMP22_Claudin (cl15797)
  PMP-22/EMP/MP20/Claudin family.
PMP22_Claudin (cl17758)
  PMP-22/EMP/MP20/Claudin family.
Claudin_2 (cl17758)
  PMP-22/EMP/MP20/Claudin tight junction.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cldn22 includes H.sapiens CLDN22 and R.norvegicus Cldn22.

 

 

 

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