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HomoloGene:133121. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HLA-F,  H.sapiens
major histocompatibility complex, class I, F
NP_001091949.1
442 aa
PATR-F,  P.troglodytes
major histocompatibility complex, class I, F
NP_001122670.1
346 aa
MAMU-F,  M.mulatta
major histocompatibility complex, class I, F
NP_001036235.2
348 aa
DLA-79,  C.lupus
MHC class Ib
NP_001018646.1
381 aa
Gm11127,  M.musculus
predicted gene 11127
NP_001186896.1
374 aa
Gm7030,  M.musculus
predicted gene 7030
NP_001170938.1
285 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

HLA-F is a surface marker on activated lymphocytes.
Lee N, et al. Eur J Immunol 40, 2308-18 (2010).
Selective export of HLA-F by its cytoplasmic tail.
Boyle LH, et al. J Immunol 176, 6464-72 (2006).
Identification of a novel HLA-F allele - HLA-F*010102.
He X, et al. Tissue Antigens 63, 181-3 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MHC_I (pfam00129)
  Class I Histocompatibility antigen, domains alpha 1 and 2.
MHC_I (cl08246)
  Class I Histocompatibility antigen, domains alpha 1 and 2.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gm11127 includes H.sapiens HLA-F.
Orthology group for M.musculus Gm7030 includes H.sapiens HLA-L.

 

 

 

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