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HomoloGene:134076. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HLA-DQA2,  H.sapiens
major histocompatibility complex, class II, DQ alpha 2
NP_064440.1
255 aa
PATR-DQA2,  P.troglodytes
major histocompatibility complex, class II, DQ alpha 2
XP_527354.1
255 aa
DLA-DQA1,  C.lupus
major histocompatibility complex, class II, DQ alpha 1
NP_001011726.1
255 aa
BOLA-DQA5,  B.taurus
major histocompatibility complex, class II, DQ alpha 5
NP_001012693.2
255 aa
hla-dqa1,  X.tropicalis
major histocompatibility complex, class II, DQ alpha 1
NP_001106538.1
245 aa
LOC100495492,  X.tropicalis
HLA class II histocompatibility antigen, DR alpha chain-like
XP_002942061.2
143 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments





Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MHC_II_alpha (cl03058)
  Class II MHC glycoproteins are expressed on the surface of antigen-presenting cells (APC), including macrophages, dendritic cells and B cells. MHC II proteins present peptide antigens that originate extracellularly from foreign bodies such as bacteria. Proteins from the pathogen are degraded into peptide fragments within the APC, which sequesters these fragments into the endosome so they can bind to MHC class II proteins, before being transported to the cell surface. MHC class II receptors display antigens for recognition by helper T cells (stimulate development of B cell clones) and inflammatory T cells (cause the release of lymphokines that attract other cells to site of infection).
Ig (cl11960)
  Immunoglobulin domain.

 

 

 

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