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HomoloGene:135932. Gene conserved in Amniota Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

Pms2,  R.norvegicus
postmeiotic segregation increased 2 (S. cerevisiae)
542 aa
PMS2,  G.gallus
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
509 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TopoII_MutL_Trans (cl02783)
  MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second ...
MutL_C (cl07336)
  MutL and MutS are key components of the DNA repair machinery that corrects replication errors. MutS recognizes mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signaling complex for repair. The N terminal region of MutL contains the ATPase domain and the C terminal is involved in dimerization.




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