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HomoloGene:140832. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GAS1,  G.gallus
growth arrest-specific 1
XP_004949280.1
314 aa
si:ch1073-459b3.2,  D.rerio
si:ch1073-459b3.2
XP_005173679.1
249 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments





Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
GDNF (cl19746)
  This cysteine rich domain is found in multiple copies in GNDF and GAS1 proteins. GDNF and neurturin (NTN) receptors are potent survival factors for sympathetic, sensory and central nervous system neurons. GDNF and neurturin promote neuronal survival by signaling through similar multicomponent receptors that consist of a common receptor tyrosine kinase and a member of a GPI-linked family of receptors that determines ligand specificity.

 

 

 

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