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HomoloGene:55636. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TNC,  H.sapiens
tenascin C
NP_002151.2
2201 aa
TNC,  P.troglodytes
tenascin C
XP_001156720.1
2201 aa
TNC,  C.lupus
tenascin C
NP_001182078.1
2201 aa
Tnc,  M.musculus
tenascin C
NP_035737.2
2019 aa
Tnc,  R.norvegicus
tenascin C
NP_446313.1
2019 aa
TNC,  G.gallus
tenascin C
NP_990787.2
1808 aa
tnc,  X.tropicalis
tenascin C
XP_004916768.1
1829 aa
LOC100149028,  D.rerio
tenascin-like
XP_005171797.1
1490 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk.
Fouda GG, et al. Proc Natl Acad Sci U S A 110, 18220-5 (2013).
The role of Tenascin C in the lymphoid progenitor cell niche.
Ellis SL, et al. Exp Hematol 41, 1050-61 (2013).
Impaired cornea wound healing in a tenascin C-deficient mouse model.
Sumioka T, et al. Lab Invest 93, 207-17 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
fn3 (pfam00041)
  Fibronectin type III domain.
EGF_2 (pfam07974)
  EGF-like domain.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
Stig1 (pfam04885)
  Stigma-specific protein, Stig1.
EGF_2 (pfam07974)
  EGF-like domain.
FN3 (cl00065)
  Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
FReD (cl00085)
  Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tnc includes H.sapiens TNC.

 

 

 

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