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HomoloGene:75133. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ADCY2,  H.sapiens
adenylate cyclase 2 (brain)
NP_065433.2
1091 aa
ADCY2,  M.mulatta
adenylate cyclase 2 (brain)
XP_001083524.1
1091 aa
ADCY2,  C.lupus
adenylate cyclase 2 (brain)
XP_535798.3
1097 aa
ADCY2,  B.taurus
adenylate cyclase 2 (brain)
XP_002696478.1
1033 aa
Adcy2,  M.musculus
adenylate cyclase 2
NP_705762.2
1095 aa
Adcy2,  R.norvegicus
adenylate cyclase 2 (brain)
NP_112269.1
1090 aa
ADCY2,  G.gallus
adenylate cyclase 2 (brain)
XP_419020.3
1096 aa
adcy2b,  D.rerio
adenylate cyclase 2b (brain)
NP_001093457.1
1139 aa
adcy2a,  D.rerio
adenylate cyclase 2a
XP_692173.5
1155 aa
Ac76E,  D.melanogaster
Adenylyl cyclase 76E
NP_524173.2
1307 aa
AgaP_AGAP010436,  A.gambiae
AgaP_AGAP010436
XP_311511.4
1250 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Structure of the adenylyl cyclase catalytic core.
Zhang G, et al. Nature 386, 247-53 (1997).
Interaction of the two cytosolic domains of mammalian adenylyl cyclase.
Whisnant RE, et al. Proc Natl Acad Sci U S A 93, 6621-5 (1996).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MFS (cd06174)
  The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
CYCc (smart00044)
  Adenylyl- / guanylyl cyclase, catalytic domain.
DUF1053 (pfam06327)
  Domain of Unknown Function (DUF1053).
DUF1053 (pfam06327)
  Domain of Unknown Function (DUF1053).
PT_UbiA (cl00337)
  UbiA family of prenyltransferases (PTases).
Nucleotidyl_cyc_III (cl11967)
  Class III nucleotidyl cyclases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Adcy2 includes H.sapiens ADCY2 and R.norvegicus Adcy2.

 

 

 

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