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HomoloGene:80163. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CTSA,  H.sapiens
cathepsin A
NP_000299.2
498 aa
CTSA,  P.troglodytes
cathepsin A
XP_001159669.2
393 aa
CTSA,  M.mulatta
cathepsin A
XP_001106032.1
494 aa
CTSA,  C.lupus
cathepsin A
NP_001103385.1
499 aa
CTSA,  B.taurus
cathepsin A
NP_001030403.1
479 aa
Ctsa,  M.musculus
cathepsin A
NP_032932.2
492 aa
Ctsa,  R.norvegicus
cathepsin A
NP_001011959.1
456 aa
CTSA,  G.gallus
cathepsin A
NP_001026662.1
471 aa
ctsa,  X.tropicalis
cathepsin A
NP_001039207.1
471 aa
ctsa,  D.rerio
cathepsin A
NP_956844.1
471 aa
F13D12.6,  C.elegans
F13D12.6
NP_496507.1
454 aa
F41C3.5,  C.elegans
F41C3.5
NP_494846.1
469 aa
PRC1,  S.cerevisiae
PRC1
NP_014026.1
532 aa
KLLA0A09977g,  K.lactis
KLLA0A09977g
XP_451436.1
535 aa
AGOS_AGL328C,  E.gossypii
AGOS_AGL328C
NP_986339.1
563 aa
cpy1,  S.pombe
cpy1
NP_594425.1
1002 aa
MGG_05663,  M.oryzae
MGG_05663
XP_003710561.1
552 aa
NCU00477,  N.crassa
NCU00477
XP_956796.1
554 aa
scpl20,  A.thaliana
scpl20
NP_193027.5
497 aa
scpl21,  A.thaliana
scpl21
NP_189169.1
505 aa
Os04g0321700,  O.sativa
Os04g0321700
NP_001052464.1
504 aa
Os12g0257000,  O.sativa
Os12g0257000
NP_001066510.1
510 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Galactosialidosis.



Publications
Articles associated with genes and sequences of this homology group.

Galactosialidosis: review and analysis of CTSA gene mutations.
Caciotti A, et al. Orphanet J Rare Dis 8, 114 (2013).
Cathepsin A is expressed in primary human antigen-presenting cells.
Reich M, et al. Immunol Lett 128, 143-7 (2010).
New mutations in two Dutch patients with early infantile galactosialidosis.
Groener J, et al. Mol Genet Metab 78, 222-8 (2003).
Expression of protective protein in human tissue.
Sohma O, et al. Pediatr Neurol 20, 210-4 (1999).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Carbpep_Y_N (pfam05388)
  Carboxypeptidase Y pro-peptide.
Peptidase_S10 (pfam00450)
  Serine carboxypeptidase.
COG2939 (COG2939)
  Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism].
Peptidase_S10 (cl08270)
  Serine carboxypeptidase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ctsa includes H.sapiens CTSA and R.norvegicus Ppgb.

 

 

 

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