Display Settings:

Format

Send to:

Choose Destination
HomoloGene:17067. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RASGEF1A,  H.sapiens
RasGEF domain family, member 1A
NP_001269791.1
489 aa
RASGEF1A,  P.troglodytes
RasGEF domain family, member 1A
XP_003312591.1
489 aa
RASGEF1A,  M.mulatta
RasGEF domain family, member 1A
XP_002805664.1
478 aa
RASGEF1A,  C.lupus
RasGEF domain family, member 1A
XP_534955.4
489 aa
RASGEF1A,  B.taurus
RasGEF domain family, member 1A
NP_001015601.1
457 aa
Rasgef1a,  M.musculus
RasGEF domain family, member 1A
NP_081802.1
489 aa
Rasgef1a,  R.norvegicus
RasGEF domain family, member 1A
XP_232315.6
564 aa
RASGEF1A,  G.gallus
RasGEF domain family, member 1A
XP_004942024.1
483 aa
rasgef1a,  X.tropicalis
RasGEF domain family, member 1A
NP_001039175.2
475 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Identifying candidate Hirschsprung disease-associated RET variants.
Burzynski GM, et al. Am J Hum Genet 76, 850-8 (2005).
Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease.
Garcia-Barcelo MM, et al. Proc Natl Acad Sci U S A 106, 2694-9 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RasGEF (cl02485)
  Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
REM (cl02520)
  Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rasgef1a includes H.sapiens RASGEF1A and R.norvegicus Rasgef1a.

 

 

 

Support Center