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HomoloGene:22482. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

MMP8,  H.sapiens
matrix metallopeptidase 8 (neutrophil collagenase)
467 aa
MMP8,  P.troglodytes
matrix metallopeptidase 8 (neutrophil collagenase)
467 aa
MMP8,  M.mulatta
matrix metallopeptidase 8 (neutrophil collagenase)
467 aa
MMP8,  C.lupus
matrix metallopeptidase 8 (neutrophil collagenase)
476 aa
MMP8,  B.taurus
matrix metallopeptidase 8 (neutrophil collagenase)
470 aa
Mmp8,  M.musculus
matrix metallopeptidase 8
465 aa
Mmp8,  R.norvegicus
matrix metallopeptidase 8
466 aa
mmp13a,  D.rerio
matrix metalloproteinase 13a
476 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Influence of MMP-8 promoter polymorphism in early osseointegrated implant failure.
Costa-Junior FR, et al. Clin Oral Investig 17, 311-6 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
HX (cd00094)
  Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
ZnMc (cl00064)
  Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mmp8 includes H.sapiens MMP8 and R.norvegicus Mmp8.




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