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HomoloGene:41531. Gene conserved in Tetrapoda

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Genes Genes identified as putative homologs of one another during the construction of HomoloGene.			Proteins Proteins used in sequence comparisons and their conserved domain architectures.
	CCDC86, H.sapiens coiled-coil domain containing 86			NP_077003.1 360 aa
	CCDC86, P.troglodytes coiled-coil domain containing 86			NP_001233482.1 360 aa
	CCDC86, M.mulatta coiled-coil domain containing 86			XP_001085103.1 360 aa
	CCDC86, B.taurus coiled-coil domain containing 86			NP_001033663.1 354 aa
	Ccdc86, M.musculus coiled-coil domain containing 86			NP_076220.2 426 aa
	Ccdc86, R.norvegicus coiled-coil domain containing 86			NP_001006975.1 341 aa
	LOC101733466, X.tropicalis coiled-coil domain-containing protein 86-like			XP_004917180.1 127 aa

Protein Alignments

Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST

Regenerate Alignments

Publications Articles associated with genes and sequences of this homology group.
Expression of Cyclon/CCDC86, a novel nuclear protein, in the hippocampus of adult non-human primates. Shishkov R, et al. J Neuroimmunol 258, 96-9 (2013).
Expression and differential response to haloperidol treatment of Cyclon/CCDC86 mRNA in schizophrenia patients. Chervenkov T, et al. Neurochem Int 62, 870-2 (2013).
Redundant promoter elements mediate IL-3-induced expression of a novel cytokine-inducible gene, cyclon. Hoshino A & Fujii H. FEBS Lett 581, 975-80 (2007).
Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon. Saint Fleur S, et al. Blood 114, 1355-65 (2009).
Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Xie G, et al. Arthritis Rheum 65, 2457-68 (2013).
Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. Ahn J, et al. J Biochem Mol Biol 37, 741-8 (2004).
Fragile X protein functions with lgl and the par complex in flies and mice. Zarnescu DC, et al. Dev Cell 8, 43-52 (2005).
Socially-responsive gene expression in male Drosophila melanogaster is influenced by the sex of the interacting partner. Ellis LL & Carney GE. Genetics 187, 157-69 (2011).
RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells. Wheeler DB, et al. Nat Methods 1, 127-32 (2004).
Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Georgas K, et al. Dev Biol 332, 273-86 (2009).

Conserved Domains Conserved Domains from CDD found in protein sequences by rpsblast searching.
PTZ00249 (PTZ00249) variable surface protein Vir28; Provisional.
PHA03247 (PHA03247) large tegument protein UL36; Provisional.
dnaA (PRK14086) chromosomal replication initiation protein; Provisional.
PAT1 (pfam09770) Topoisomerase II-associated protein PAT1.

Related Homology Resources Links to curated and computed homology information found in other databases.
MGI:1277220 Orthology group for M.musculus Ccdc86 includes H.sapiens CCDC86 and R.norvegicus Ccdc86.

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