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HomoloGene:4383. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MANF,  H.sapiens
mesencephalic astrocyte-derived neurotrophic factor
NP_006001.3
182 aa
MANF,  P.troglodytes
mesencephalic astrocyte-derived neurotrophic factor
XP_001169644.3
246 aa
LOC700659,  M.mulatta
mesencephalic astrocyte-derived neurotrophic factor-like
XP_002802839.1
258 aa
MANF,  C.lupus
mesencephalic astrocyte-derived neurotrophic factor
XP_003639808.2
223 aa
MANF,  B.taurus
mesencephalic astrocyte-derived neurotrophic factor
NP_001094681.1
179 aa
Manf,  M.musculus
mesencephalic astrocyte-derived neurotrophic factor
NP_083379.2
179 aa
manf,  X.tropicalis
mesencephalic astrocyte-derived neurotrophic factor
NP_001016425.1
180 aa
manf,  D.rerio
mesencephalic astrocyte-derived neurotrophic factor
NP_001070097.1
180 aa
Manf,  D.melanogaster
Mesencephalic astrocyte-derived neurotrophic factor
NP_477445.1
173 aa
AgaP_AGAP003016,  A.gambiae
AgaP_AGAP003016
XP_311862.3
180 aa
Y54G2A.23,  C.elegans
Y54G2A.23
NP_500273.2
168 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Pancreatic cancer.



Publications
Articles associated with genes and sequences of this homology group.

Solution structure and dynamics of mouse ARMET.
Hoseki J, et al. FEBS Lett 584, 1536-42 (2010).
Novel CDNF/MANF family of neurotrophic factors.
Lindholm P & Saarma M. Dev Neurobiol 70, 360-71 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Armet (pfam10208)
  Degradation arginine-rich protein for mis-folding.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Manf includes H.sapiens MANF and R.norvegicus Armet.

 

 

 

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