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HomoloGene:55467. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FBP1,  H.sapiens
fructose-1,6-bisphosphatase 1
NP_001121100.1
338 aa
FBP1,  P.troglodytes
fructose-1,6-bisphosphatase 1
XP_520717.2
338 aa
FBP1,  M.mulatta
fructose-1,6-bisphosphatase 1
XP_001105272.1
338 aa
FBP1,  C.lupus
fructose-1,6-bisphosphatase 1
XP_848306.1
338 aa
FBP1,  B.taurus
fructose-1,6-bisphosphatase 1
NP_001029619.1
338 aa
Fbp1,  M.musculus
fructose bisphosphatase 1
NP_062268.1
338 aa
Fbp1,  R.norvegicus
fructose-1,6-bisphosphatase 1
NP_036690.2
363 aa
FBP1,  G.gallus
fructose-1,6-bisphosphatase 1
NP_001264977.1
339 aa
fbp1,  X.tropicalis
fructose-1,6-bisphosphatase 1
NP_989145.1
338 aa
fbp1b,  D.rerio
fructose-1,6-bisphosphatase 1b
NP_998297.1
337 aa
fbp1a,  D.rerio
fructose-1,6-bisphosphatase 1a
NP_956236.1
337 aa
FBP1,  S.cerevisiae
FBP1
NP_013481.3
348 aa
KLLA0E01211g,  K.lactis
KLLA0E01211g
XP_454003.1
355 aa
AGOS_AFR593C,  E.gossypii
AGOS_AFR593C
NP_986140.2
342 aa
fbp1,  S.pombe
fbp1
NP_595083.2
347 aa
MGG_08895,  M.oryzae
MGG_08895
XP_003713924.1
344 aa
NCU04797,  N.crassa
NCU04797
XP_960423.1
350 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fructose-bisphosphatase deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Novel fructose-1,6-bisphosphatase gene mutation in two siblings.
Eren E, et al. DNA Cell Biol 32, 635-9 (2013).
Structure of E69Q mutant of human muscle fructose-1,6-bisphosphatase.
Zarzycki M, et al. Acta Crystallogr D Biol Crystallogr 67, 1028-34 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FIG (cl00289)
  FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fbp1 includes H.sapiens FBP1 and R.norvegicus Fbp1.

 

 

 

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