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HomoloGene:7240. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

BACH2,  H.sapiens
BTB and CNC homology 1, basic leucine zipper transcription factor 2
NP_001164265.1
841 aa
BACH2,  P.troglodytes
BTB and CNC homology 1, basic leucine zipper transcription factor 2
XP_003339186.1
830 aa
BACH2,  M.mulatta
BTB and CNC homology 1, basic leucine zipper transcription factor 2
XP_001098717.1
842 aa
BACH2,  C.lupus
BTB and CNC homology 1, basic leucine zipper transcription factor 2
XP_539044.3
856 aa
BACH2,  B.taurus
BTB and CNC homology 1, basic leucine zipper transcription factor 2
XP_002690235.2
851 aa
Bach2,  M.musculus
BTB and CNC homology 2
NP_001103131.1
839 aa
RGD1562865,  R.norvegicus
similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2
NP_001129226.1
839 aa
BACH2,  G.gallus
BTB and CNC homology 1, basic leucine zipper transcription factor 2
XP_419833.2
824 aa
bach2,  X.tropicalis
BTB and CNC homology 1, basic leucine zipper transcription factor 2
XP_002940359.1
829 aa
bach2b,  D.rerio
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
XP_005160605.1
823 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Bach2 maintains T cells in a naive state by suppressing effector memory-related genes.
Tsukumo S, et al. Proc Natl Acad Sci U S A 110, 10735-40 (2013).
The structure of the Bach2 POZ-domain dimer reveals an intersubunit disulfide bond.
Rosbrook GO, et al. Acta Crystallogr D Biol Crystallogr 68, 26-34 (2012).
The role of Bach2 in nucleic acid-triggered antiviral innate immune responses.
Hong SW, et al. Biochem Biophys Res Commun 365, 426-32 (2008).
Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemic cells.
Ono A, et al. Genes Chromosomes Cancer 46, 67-74 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
BTB (pfam00651)
  BTB/POZ domain.
BTB (cl02518)
  BTB/POZ domain.
B_zip1 (cl02576)
  basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Bach2 includes H.sapiens BACH2.

 

 

 

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