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HomoloGene:88882. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

HIST1H2AJ,  H.sapiens
histone cluster 1, H2aj
128 aa
LOC737087,  P.troglodytes
histone H2A type 1-J-like
128 aa
HIST1H2AJ,  M.mulatta
histone cluster 1, H2aj
128 aa
LOC488304,  C.lupus
histone H2A type 1-E-like
145 aa
HIST1H2AJ,  B.taurus
histone cluster 1, H2aj
128 aa
Hist1h2af,  M.musculus
histone cluster 1, H2af
130 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Prothymosin alpha binds histones in vitro and shows activity in nucleosome assembly assay.
Díaz-Jullien C, et al. Biochim Biophys Acta 1296, 219-27 (1996).
The human H2A and H2B histone gene complement.
Albig W, et al. Biol Chem 380, 7-18 (1999).
The human histone gene cluster at the D6S105 locus.
Albig W & Doenecke D. Hum Genet 101, 284-94 (1997).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PTZ00017 (PTZ00017)
  histone H2A; Provisional.
H2A (cd00074)
  Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hist1h2af includes H.sapiens HIST1H2AL and R.norvegicus RGD1564767.




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