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HomoloGene:9905. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TPCN1,  H.sapiens
two pore segment channel 1
NP_001137291.1
888 aa
TPCN1,  P.troglodytes
two pore segment channel 1
XP_003313998.1
888 aa
TPCN1,  M.mulatta
two pore segment channel 1
XP_002798827.1
903 aa
TPCN1,  C.lupus
two pore segment channel 1
XP_534690.2
819 aa
TPCN1,  B.taurus
two pore segment channel 1
XP_002694563.1
816 aa
Tpcn1,  M.musculus
two pore channel 1
NP_665852.1
817 aa
Tpcn1,  R.norvegicus
two pore segment channel 1
NP_647548.2
817 aa
TPCN1,  G.gallus
two pore segment channel 1
XP_004934547.1
817 aa
tpcn1,  X.tropicalis
two pore segment channel 1
XP_002934333.2
805 aa
tpcn1,  D.rerio
two pore segment channel 1
XP_005165277.1
805 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Calcium signaling via two-pore channels: local or global, that is the question.
Zhu MX, et al. Am J Physiol Cell Physiol 298, C430-41 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ion_trans (pfam00520)
  Ion transport protein.
Ion_trans (pfam00520)
  Ion transport protein.
TMF_TATA_bd (pfam12325)
  TATA element modulatory factor 1 TATA binding.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tpcn1 includes H.sapiens TPCN1 and R.norvegicus Tpcn1.

 

 

 

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