Display Settings:

Format

Send to:

Choose Destination

Links from Gene

HomoloGene:32236. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SV2B,  H.sapiens
synaptic vesicle glycoprotein 2B
NP_055663.1
683 aa
SV2B,  M.mulatta
synaptic vesicle glycoprotein 2B
XP_001099688.2
683 aa
SV2B,  C.lupus
synaptic vesicle glycoprotein 2B
XP_545841.2
713 aa
SV2B,  B.taurus
synaptic vesicle glycoprotein 2B
NP_001076917.1
683 aa
Sv2b,  M.musculus
synaptic vesicle glycoprotein 2 b
NP_705807.2
683 aa
Sv2b,  R.norvegicus
synaptic vesicle glycoprotein 2b
NP_476555.1
683 aa
SV2B,  G.gallus
synaptic vesicle glycoprotein 2B
XP_004943918.1
705 aa
sv2b,  X.tropicalis
synaptic vesicle glycoprotein 2B
XP_004912713.1
711 aa
sv2ba,  D.rerio
synaptic vesicle glycoprotein 2 ba
NP_001076464.1
689 aa
LOC101883740,  D.rerio
synaptic vesicle glycoprotein 2B-like
XP_005161575.1
687 aa
sv2bb,  D.rerio
synaptic vesicle glycoprotein 2 bb
XP_005174356.1
687 aa
SPAPB1E7.08c,  S.pombe
SPAPB1E7.08c
NP_594134.1
554 aa
MGG_00201,  M.oryzae
MGG_00201
XP_003718914.1
464 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Brain synaptic junctional proteins at the acrosome of rat testicular germ cells.
Redecker P, et al. J Histochem Cytochem 51, 809-19 (2003).
SV2 mediates entry of tetanus neurotoxin into central neurons.
Yeh FL, et al. PLoS Pathog 6, e1001207 (2010).
SV2 regulates neurotransmitter release via multiple mechanisms.
Nowack A, et al. Am J Physiol Cell Physiol 299, C960-7 (2010).
SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis.
Chang WP & S├╝dhof TC. J Neurosci 29, 883-97 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MFS (cd06174)
  The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
synapt_SV2 (TIGR01299)
  synaptic vesicle protein SV2.
Pentapeptide_4 (pfam13599)
  Pentapeptide repeats (9 copies).
MFS_1 (pfam07690)
  Major Facilitator Superfamily.
Pentapeptide_4 (pfam13599)
  Pentapeptide repeats (9 copies).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sv2b includes H.sapiens SV2B and R.norvegicus Sv2b.

 

 

 

Support Center