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HomoloGene:3812. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MAP3K8,  H.sapiens
mitogen-activated protein kinase kinase kinase 8
NP_005195.2
467 aa
MAP3K8,  P.troglodytes
mitogen-activated protein kinase kinase kinase 8
XP_001137395.1
467 aa
MAP3K8,  C.lupus
mitogen-activated protein kinase kinase kinase 8
XP_544213.3
467 aa
MAP3K8,  B.taurus
mitogen-activated protein kinase kinase kinase 8
NP_001092541.1
468 aa
Map3k8,  M.musculus
mitogen-activated protein kinase kinase kinase 8
NP_031772.1
467 aa
Map3k8,  R.norvegicus
mitogen-activated protein kinase kinase kinase 8
NP_446299.1
467 aa
MAP3K8,  G.gallus
mitogen-activated protein kinase kinase kinase 8
XP_418581.3
487 aa
map3k8,  X.tropicalis
mitogen-activated protein kinase kinase kinase 8
XP_002940379.1
481 aa
map3k8,  D.rerio
mitogen-activated protein kinase kinase kinase 8
XP_692177.3
472 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Lung cancer, somatic.



Publications
Articles associated with genes and sequences of this homology group.

Tpl2 knockout keratinocytes have increased biomarkers for invasion and metastasis.
Decicco-Skinner KL, et al. Carcinogenesis 34, 2789-98 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Map3k8 includes H.sapiens MAP3K8 and R.norvegicus Map3k8.


 

 

 

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