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HomoloGene:3508. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

PTGDR2,  H.sapiens
prostaglandin D2 receptor 2
395 aa
GPR44,  P.troglodytes
G protein-coupled receptor 44
397 aa
GPR44,  M.mulatta
prostaglandin D2 receptor 2
396 aa
GPR44,  C.lupus
G protein-coupled receptor 44
400 aa
GPR44,  B.taurus
G protein-coupled receptor 44
411 aa
Gpr44,  M.musculus
G protein-coupled receptor 44
382 aa
Ptgdr2,  R.norvegicus
prostaglandin D2 receptor 2
403 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis.
Ito H, et al. J Am Soc Nephrol 23, 1797-809 (2012).
Roles of CRTH2+ CD4+ T cells in immunoglobulin G4-related lacrimal gland enlargement.
Saito Y, et al. Int Arch Allergy Immunol 158 Suppl 1, 42-6 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gpr44 includes H.sapiens PTGDR2 and R.norvegicus Gpr44.




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