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Links from GEO Profiles

HomoloGene:4138. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

TRAF1,  H.sapiens
TNF receptor-associated factor 1
416 aa
TRAF1,  P.troglodytes
TNF receptor-associated factor 1
416 aa
TRAF1,  M.mulatta
TNF receptor-associated factor 1
416 aa
TRAF1,  C.lupus
TNF receptor-associated factor 1
413 aa
TRAF1,  B.taurus
TNF receptor-associated factor 1
415 aa
Traf1,  M.musculus
TNF receptor-associated factor 1
409 aa
Traf1,  R.norvegicus
TNF receptor-associated factor 1
409 aa
TRAF1,  G.gallus
TNF receptor-associated factor 1
599 aa
traf1,  D.rerio
TNF receptor-associated factor 1
551 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

TRAF1-C5 affects quality of life in patients with primary biliary cirrhosis.
Raszeja-Wyszomirska J, et al. Clin Dev Immunol 2013, 510547 (2013).
TRAF1 phosphorylation on Serine 139 modulates NF-κB activity downstream of 4-1BB in T cells.
Oussa NA, et al. Biochem Biophys Res Commun 432, 129-34 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-TRAF (pfam02176)
  TRAF-type zinc finger.
MATH (cl02446)
  MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Traf1 includes H.sapiens TRAF1.




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