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HomoloGene:26615. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SHROOM4,  H.sapiens
shroom family member 4
NP_065768.2
1493 aa
SHROOM4,  P.troglodytes
shroom family member 4
XP_003317511.1
1549 aa
SHROOM4,  M.mulatta
shroom family member 4
XP_001083331.2
1531 aa
SHROOM4,  C.lupus
shroom family member 4
XP_855411.2
1483 aa
SHROOM4,  B.taurus
shroom family member 4
XP_002700130.1
1495 aa
Shroom4,  M.musculus
shroom family member 4
NP_001035549.1
1475 aa
Shroom4,  R.norvegicus
shroom family member 4
NP_001178659.1
1487 aa
LOC777072,  G.gallus
protein Shroom2-like
XP_003641181.2
1041 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Stocco dos Santos X-linked mental retardation syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Shroom4 (Kiaa1202) is an actin-associated protein implicated in cytoskeletal organization.
Yoder M & Hildebrand JD. Cell Motil Cytoskeleton 64, 49-63 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ASD2 (pfam08687)
  Apx/Shroom domain ASD2.
ASD2 (pfam08687)
  Apx/Shroom domain ASD2.
PDZ (cl00117)
  PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Shroom4 includes H.sapiens SHROOM4 and R.norvegicus Shroom4.

 

 

 

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