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Links from GEO Profiles

HomoloGene:16987. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

GPSM1,  H.sapiens
G-protein signaling modulator 1
675 aa
GPSM1,  C.lupus
G-protein signaling modulator 1
704 aa
GPSM1,  B.taurus
G-protein signaling modulator 1
705 aa
Gpsm1,  M.musculus
G-protein signalling modulator 1 (AGS3-like, C. elegans)
705 aa
Gpsm1,  R.norvegicus
G-protein signaling modulator 1
673 aa
GPSM1,  G.gallus
G-protein signaling modulator 1
701 aa
gpsm1,  X.tropicalis
G-protein signaling modulator 1
658 aa
gpsm1b,  D.rerio
G-protein signaling modulator 1b
634 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.
Nadella R, et al. J Am Soc Nephrol 21, 1275-80 (2010).
A specific role of AGS3 in the surface expression of plasma membrane proteins.
Groves B, et al. Proc Natl Acad Sci U S A 104, 18103-8 (2007).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
GoLoco (pfam02188)
  GoLoco motif.
TPR_12 (pfam13424)
  Tetratricopeptide repeat.
TPR (cd00189)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR_12 (pfam13424)
  Tetratricopeptide repeat.
GoLoco (cl12112)
  GEF specific for Galpha_i proteins

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gpsm1 includes H.sapiens GPSM1 and R.norvegicus Gpsm1.




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