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HomoloGene:116010. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

YPEL3,  H.sapiens
yippee-like 3 (Drosophila)
NP_113665.3
157 aa
YPEL3,  P.troglodytes
yippee-like 3 (Drosophila)
XP_003952871.1
119 aa
LOC708740,  M.mulatta
protein yippee-like 3-like
XP_001108654.1
119 aa
YPEL3,  C.lupus
yippee-like 3 (Drosophila)
XP_003434860.2
169 aa
YPEL3,  B.taurus
yippee-like 3 (Drosophila)
NP_001192338.1
119 aa
Ypel3,  M.musculus
yippee-like 3 (Drosophila)
NP_079623.1
119 aa
Ypel3,  R.norvegicus
yippee-like 3 (Drosophila)
NP_001129170.1
119 aa
LOC561851,  D.rerio
protein yippee-like 1-like
XP_690346.1
119 aa
F37A8.5,  C.elegans
F37A8.5
NP_497796.1
137 aa
MOH1,  S.cerevisiae
MOH1
NP_009504.1
138 aa
KLLA0E05875g,  K.lactis
KLLA0E05875g
XP_454211.1
124 aa
AGOS_ABR153C,  E.gossypii
AGOS_ABR153C
NP_983101.1
124 aa
SPAPJ691.02,  S.pombe
SPAPJ691.02
NP_594895.1
131 aa
NCU00024,  N.crassa
NCU00024
XP_957011.1
227 aa
AT3G11230,  A.thaliana
AT3G11230
NP_566389.1
129 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Senescence-associated gene YPEL3 is downregulated in human colon tumors.
Tuttle R, et al. Ann Surg Oncol 18, 1791-6 (2011).
YPEL3, a p53-regulated gene that induces cellular senescence.
Kelley KD, et al. Cancer Res 70, 3566-75 (2010).
Why YPEL3 represents a novel tumor suppressor.
Berberich SJ, et al. Front Biosci (Landmark Ed) 16, 1746-51 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Yippee (pfam03226)
  Yippee putative zinc-binding protein.
Yippee-Mis18 (pfam03226)
  Yippee zinc-binding/DNA-binding /Mis18, centromere assembly.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ypel3 includes H.sapiens YPEL3 and R.norvegicus RGD1564579.

 

 

 

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