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HomoloGene:4903. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

AKAP13,  H.sapiens
A kinase (PRKA) anchor protein 13
2817 aa
AKAP13,  P.troglodytes
A kinase (PRKA) anchor protein 13
2813 aa
AKAP13,  M.mulatta
A kinase (PRKA) anchor protein 13
2756 aa
AKAP13,  C.lupus
A kinase (PRKA) anchor protein 13
2848 aa
Akap13,  M.musculus
A kinase (PRKA) anchor protein 13
2776 aa
Akap13,  R.norvegicus
A kinase (PRKA) anchor protein 13
2760 aa
AKAP13,  G.gallus
A kinase (PRKA) anchor protein 13
1492 aa
akap13,  X.tropicalis
A kinase (PRKA) anchor protein 13
2576 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade.
Smith FD, et al. Nat Cell Biol 12, 1242-9 (2010).
Resonance assignments of the human AKAP13-PH domain and stabilizing DH helix.
Sugawara M, et al. Biomol NMR Assign 3, 215-8 (2009).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
C1 (cl00040)
  Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
RhoGEF (cl02571)
  Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
PH-like (cl17171)
  Pleckstrin homology-like domain.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Akap13 includes H.sapiens AKAP13 and R.norvegicus Akap13.




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