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HomoloGene:4903. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

AKAP13,  H.sapiens
A kinase (PRKA) anchor protein 13
NP_006729.4
2817 aa
AKAP13,  P.troglodytes
A kinase (PRKA) anchor protein 13
XP_001163836.1
2813 aa
AKAP13,  M.mulatta
A kinase (PRKA) anchor protein 13
XP_001086697.2
2756 aa
AKAP13,  C.lupus
A kinase (PRKA) anchor protein 13
XP_005618390.1
2848 aa
Akap13,  M.musculus
A kinase (PRKA) anchor protein 13
NP_083608.1
2776 aa
Akap13,  R.norvegicus
A kinase (PRKA) anchor protein 13
NP_001099741.2
2760 aa
AKAP13,  G.gallus
A kinase (PRKA) anchor protein 13
XP_004943916.1
1492 aa
akap13,  X.tropicalis
A kinase (PRKA) anchor protein 13
XP_004912711.1
2576 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade.
Smith FD, et al. Nat Cell Biol 12, 1242-9 (2010).
Resonance assignments of the human AKAP13-PH domain and stabilizing DH helix.
Sugawara M, et al. Biomol NMR Assign 3, 215-8 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
C1 (cl00040)
  Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
RhoGEF (cl02571)
  Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
PH-like (cl17171)
  Pleckstrin homology-like domain.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Akap13 includes H.sapiens AKAP13 and R.norvegicus Akap13.

 

 

 

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