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HomoloGene:27862. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ATP11C,  H.sapiens
ATPase, class VI, type 11C
NP_775965.2
1132 aa
ATP11C,  P.troglodytes
ATPase, class VI, type 11C
XP_003954150.1
1125 aa
ATP11C,  M.mulatta
ATPase, class VI, type 11C
XP_001084697.1
1119 aa
ATP11C,  C.lupus
ATPase, class VI, type 11C
XP_003435587.1
1132 aa
ATP11C,  B.taurus
ATPase, class VI, type 11C
XP_002699621.1
1119 aa
Atp11c,  M.musculus
ATPase, class VI, type 11C
NP_001032952.1
1129 aa
Atp11c,  R.norvegicus
ATPase, class VI, type 11C
XP_006257658.1
1129 aa
ATP11C,  G.gallus
ATPase, class VI, type 11C
XP_004940743.1
1226 aa
LOC100498300,  X.tropicalis
probable phospholipid-transporting ATPase 11C-like
XP_002932642.2
1127 aa
atp11c,  D.rerio
ATPase, Class VI, type 11C
XP_005173285.1
1153 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Genome-wide ENU mutagenesis to reveal immune regulators.
Nelms KA & Goodnow CC. Immunity 15, 409-18 (2001).
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C.
Siggs OM, et al. Proc Natl Acad Sci U S A 108, 7890-5 (2011).
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
Arnold CN, et al. Proc Natl Acad Sci U S A 109, 12286-93 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
E1-E2_ATPase (pfam00122)
  E1-E2 ATPase.
Hydrolase_like2 (pfam13246)
  Putative hydrolase of sodium-potassium ATPase alpha subunit.
PI-PLCc_GDPD_SF (cl14615)
  Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily.
E1-E2_ATPase (pfam00122)
  E1-E2 ATPase.
Hydrolase_like2 (pfam13246)
  Putative hydrolase of sodium-potassium ATPase alpha subunit.
DUF2269 (cl02335)
  Predicted integral membrane protein (DUF2269).
7TMR-DISM_7TM (cl09440)
  7TM diverse intracellular signalling.
HAD (cl19137)
  haloacid dehalogenase-like hydrolase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atp11c includes H.sapiens ATP11C.


 

 

 

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