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Links from GEO Profiles

HomoloGene:10571. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ASCL3,  H.sapiens
achaete-scute family bHLH transcription factor 3
NP_065697.1
181 aa
ASCL3,  P.troglodytes
achaete-scute complex homolog 3 (Drosophila)
XP_522303.2
181 aa
ASCL3,  M.mulatta
achaete-scute complex homolog 3 (Drosophila)
XP_001102401.1
181 aa
ASCL3,  C.lupus
achaete-scute complex homolog 3 (Drosophila)
XP_005633695.1
181 aa
ASCL3,  B.taurus
achaete-scute complex homolog 3 (Drosophila)
XP_005216164.1
181 aa
Ascl3,  M.musculus
achaete-scute complex homolog 3 (Drosophila)
NP_064435.1
174 aa
Ascl3,  R.norvegicus
achaete-scute family bHLH transcription factor 3
NP_001258163.1
174 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Hash4, a novel human achaete-scute homologue found in fetal skin.
Jonsson M, et al. Genomics 84, 859-66 (2004).
Ascl1 is required for oligodendrocyte development in the spinal cord.
Sugimori M, et al. Development 135, 1271-81 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ascl3 includes H.sapiens ASCL3 and R.norvegicus Ascl3.

 

 

 

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