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HomoloGene:40119. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ING1,  H.sapiens
inhibitor of growth family, member 1
NP_937862.1
279 aa
ING1,  P.troglodytes
inhibitor of growth family, member 1
XP_001139907.1
279 aa
ING1,  M.mulatta
inhibitor of growth family, member 1
XP_001084274.1
279 aa
LOC478381,  C.lupus
inhibitor of growth protein 1-like
XP_005638810.1
279 aa
ING1,  C.lupus
inhibitor of growth family, member 1
XP_534185.1
279 aa
ING1,  B.taurus
inhibitor of growth family, member 1
NP_001071382.1
278 aa
Ing1,  M.musculus
inhibitor of growth family, member 1
NP_036049.2
279 aa
Ing1,  R.norvegicus
inhibitor of growth family, member 1
NP_001033680.1
279 aa
ING1,  G.gallus
inhibitor of growth family, member 1
XP_416956.4
237 aa
ing1,  X.tropicalis
inhibitor of growth family, member 1
NP_001090790.1
279 aa
ing1,  D.rerio
inhibitor of growth family, member 1
NP_001035446.1
309 aa
CG7379,  D.melanogaster
CG7379
NP_650656.1
433 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Squamous cell carcinoma, head and neck.



Publications
Articles associated with genes and sequences of this homology group.

ING1 induces apoptosis through direct effects at the mitochondria.
Bose P, et al. Cell Death Dis 4, e788 (2013).
Inhibitor of growth 1 (ING1) acts at early steps of multiple DNA repair pathways.
Ceruti JM, et al. Mol Cell Biochem 378, 117-26 (2013).
[Mutation of ING1 gene in laryngeal squamous cell carcinoma and its association with p33ING1b protein expression].
Li F, et al. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 25, 986-9 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHD (pfam00628)
  PHD-finger.
ING (pfam12998)
  Inhibitor of growth proteins N-terminal histone-binding.
ING (pfam12998)
  Inhibitor of growth proteins N-terminal histone-binding.
PHD (cl17445)
  PHD-finger.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ing1 includes H.sapiens ING1 and R.norvegicus Ing1.

 

 

 

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