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HomoloGene:37295. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

TTPA,  H.sapiens
tocopherol (alpha) transfer protein
278 aa
TTPA,  P.troglodytes
tocopherol (alpha) transfer protein
278 aa
TTPA,  M.mulatta
tocopherol (alpha) transfer protein
278 aa
TTPA,  C.lupus
tocopherol (alpha) transfer protein
226 aa
TTPA,  B.taurus
tocopherol (alpha) transfer protein
282 aa
Ttpa,  M.musculus
tocopherol (alpha) transfer protein
278 aa
Ttpa,  R.norvegicus
tocopherol (alpha) transfer protein
278 aa
TTPA,  G.gallus
tocopherol (alpha) transfer protein
277 aa
ttpa,  D.rerio
tocopherol (alpha) transfer protein
285 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Ataxia with isolated vitamin E deficiency.

Articles associated with genes and sequences of this homology group.

Tocopherol transfer protein sensitizes prostate cancer cells to vitamin E.
Morley S, et al. J Biol Chem 285, 35578-89 (2010).
Ataxia with Vitamin E Deficiency
Schuelke M, et al. (1993).
Ataxia with vitamin E deficiency associated with deafness.
Kara B, et al. Turk J Pediatr 50, 471-5 (2008).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CRAL_TRIO_N (pfam03765)
  CRAL/TRIO, N-terminal domain.
SEC14 (cl15787)
  Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
CRAL_TRIO_N (cl16919)
  This all-alpha domain is found to the N-terminus of pfam00650.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ttpa includes H.sapiens TTPA and R.norvegicus Ttpa.




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