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HomoloGene:10094. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NEIL3,  H.sapiens
nei endonuclease VIII-like 3 (E. coli)
NP_060718.2
605 aa
NEIL3,  P.troglodytes
nei endonuclease VIII-like 3 (E. coli)
XP_526741.2
606 aa
NEIL3,  M.mulatta
nei endonuclease VIII-like 3 (E. coli)
XP_001090459.1
602 aa
NEIL3,  C.lupus
nei endonuclease VIII-like 3 (E. coli)
XP_532852.3
604 aa
NEIL3,  B.taurus
nei endonuclease VIII-like 3 (E. coli)
NP_001029662.1
606 aa
Neil3,  M.musculus
nei like 3 (E. coli)
NP_666320.1
606 aa
Neil3,  R.norvegicus
nei endonuclease VIII-like 3 (E. coli)
NP_001163817.1
606 aa
NEIL3,  G.gallus
nei endonuclease VIII-like 3 (E. coli)
XP_426306.3
585 aa
neil3,  X.tropicalis
nei endonuclease VIII-like 3
NP_001017201.1
574 aa
neil3,  D.rerio
nei endonuclease VIII-like 3 (E. coli)
NP_001007336.1
550 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo.
Liu M, et al. Proc Natl Acad Sci U S A 107, 4925-30 (2010).
Expression and purification of NEIL3, a human DNA glycosylase homolog.
Krokeide SZ, et al. Protein Expr Purif 65, 160-4 (2009).
Expression and purification of active mouse and human NEIL3 proteins.
Liu M, et al. Protein Expr Purif 84, 130-9 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
H2TH (pfam06831)
  Formamidopyrimidine-DNA glycosylase H2TH domain.
zf-RanBP (pfam00641)
  Zn-finger in Ran binding protein and others.
zf-GRF (pfam06839)
  GRF zinc finger.
zf-GRF (pfam06839)
  GRF zinc finger.
zf-RanBP (cl02656)
  Zn-finger in Ran binding protein and others.
FpgNei_N (cl03119)
  N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Neil3 includes H.sapiens NEIL3 and R.norvegicus Neil3.


 

 

 

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