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HomoloGene:113382. Gene exclusive to M.musculus Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

Defa23,  M.musculus
defensin, alpha, 23
NP_001012307.1
93 aa
Defa2,  M.musculus
defensin, alpha, 2
NP_001182563.2
95 aa
Gm21002,  M.musculus
predicted gene, 21002
NP_001257484.1
95 aa
Defa21,  M.musculus
defensin, alpha, 21
NP_899076.1
93 aa
Defa22,  M.musculus
defensin, alpha, 22
NP_997541.2
93 aa
Gm10104,  M.musculus
predicted gene 10104
NP_001170952.1
93 aa
Gm21498,  M.musculus
predicted gene, 21498
NP_001257542.1
93 aa
Defa25,  M.musculus
defensin, alpha, 25
NP_031875.1
92 aa
Gm15299,  M.musculus
predicted pseudogene 15299
NP_001164426.1
93 aa
Gm15284,  M.musculus
predicted gene 15284
NP_001170956.1
93 aa
Defa24,  M.musculus
defensin, alpha, 24
NP_001019396.1
93 aa
Defa-rs7,  M.musculus
defensin, alpha, related sequence 7
NP_031874.2
93 aa
Defa17,  M.musculus
defensin, alpha, 17
NP_001161262.1
93 aa
Gm15293,  M.musculus
predicted gene 15293
NP_001170957.1
93 aa
Gm14850,  M.musculus
predicted gene 14850
NP_001170993.1
93 aa
Gm15292,  M.musculus
predicted gene 15292
NP_001170958.1
93 aa
Defa26,  M.musculus
defensin, alpha, 26
NP_001073402.1
93 aa
Defa3,  M.musculus
defensin, alpha, 3
NP_031876.1
93 aa
Gm6696,  M.musculus
predicted gene 6696
NP_001170994.1
94 aa
Gm15315,  M.musculus
predicted gene 15315
NP_001170999.1
93 aa
Defa5,  M.musculus
defensin, alpha, 5
NP_031877.2
93 aa
Gm15308,  M.musculus
predicted gene 15308
NP_001170992.1
95 aa
Defa20,  M.musculus
defensin, alpha, 20
NP_899091.2
95 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cryptdin 3 forms anion selective channels in cytoplasmic membranes of human embryonic kidney cells.
Yue G, et al. Am J Physiol Gastrointest Liver Physiol 282, G757-65 (2002).
Induction of a rat enteric defensin gene by hemorrhagic shock.
Condon MR, et al. Infect Immun 67, 4787-93 (1999).
Activation of Paneth cell alpha-defensins in mouse small intestine.
Ayabe T, et al. J Biol Chem 277, 5219-28 (2002).
A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells.
Garabedian EM, et al. Proc Natl Acad Sci U S A 95, 15382-7 (1998).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Defensin_propep (pfam00879)
  Defensin propeptide.
Defensin_beta (pfam00711)
  Beta defensin.
Defensin_1 (cl11590)
  Cysteine-rich domains that lyse bacteria, fungi and enveloped viruses by forming multimeric membrane-spanning channels.


 

 

 

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