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Links from Nucleotide

HomoloGene:21237. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GZMA,  H.sapiens
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
NP_006135.1
262 aa
GZMA,  P.troglodytes
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
XP_001148261.1
262 aa
GZMA,  M.mulatta
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
XP_001097639.1
262 aa
GZMA,  C.lupus
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
XP_544335.3
270 aa
GZMA,  B.taurus
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
NP_001092565.1
259 aa
Gzma,  M.musculus
granzyme A
NP_034500.1
260 aa
Gzma,  R.norvegicus
granzyme A
NP_703198.1
261 aa
GZMA,  G.gallus
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
NP_989788.1
260 aa
LOC100497188,  X.tropicalis
granzyme A-like
XP_002941159.1
266 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The substrate specificity profile of human granzyme A.
Van Damme P, et al. Biol Chem 391, 983-97 (2010).
Granzyme A is a proinflammatory protease.
Pardo J, et al. Blood 114, 3968; author reply 3969-70 (2009).
A role of a lymphocyte tryptase, granzyme A, in experimental ulcerative colitis.
Hirayasu H, et al. Biosci Biotechnol Biochem 71, 234-7 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tryp_SPc (cd00190)
  Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gzma includes H.sapiens GZMA and R.norvegicus Gzma.


 

 

 

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