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Links from Nucleotide

HomoloGene:55434. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

COL5A1,  H.sapiens
collagen, type V, alpha 1
1838 aa
Col5a1,  M.musculus
collagen, type V, alpha 1
1838 aa
Col5a1,  R.norvegicus
collagen, type V, alpha 1
1840 aa
COL5A1,  G.gallus
collagen, type V, alpha 1
1835 aa
col5a1,  X.tropicalis
collagen, type V, alpha 1
1865 aa
col5a1,  D.rerio
procollagen, type V, alpha 1
2118 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Ehlers-Danlos syndrome, type I.
Ehlers-Danlos syndrome, type II.

Articles associated with genes and sequences of this homology group.

The COL5A1 gene, ultra-marathon running performance, and range of motion.
Brown JC, et al. Int J Sports Physiol Perform 6, 485-96 (2011).
Type V collagen genotype and exercise-related phenotype relationships: a novel hypothesis.
Collins M & Posthumus M. Exerc Sport Sci Rev 39, 191-8 (2011).
Range of motion measurements diverge with increasing age for COL5A1 genotypes.
Brown JC, et al. Scand J Med Sci Sports 21, e266-72 (2011).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TSPN (smart00210)
  Thrombospondin N-terminal -like domains.
COLFI (cl02436)
  Fibrillar collagen C-terminal domain.
LamG (cl17353)
  Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
Collagen (cl19732)
  Collagen triple helix repeat (20 copies).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Col5a1 includes H.sapiens COL5A1 and R.norvegicus Col5a1.




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