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Links from Nucleotide

HomoloGene:20489. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HCK,  H.sapiens
hemopoietic cell kinase
NP_002101.2
526 aa
HCK,  P.troglodytes
hemopoietic cell kinase
XP_514571.3
509 aa
LOC715723,  M.mulatta
tyrosine-protein kinase HCK-like
XP_002798221.1
504 aa
HCK,  C.lupus
hemopoietic cell kinase
XP_542952.2
627 aa
HCK,  B.taurus
hemopoietic cell kinase
NP_001103664.1
524 aa
Hck,  M.musculus
hemopoietic cell kinase
NP_034537.2
524 aa
Hck,  R.norvegicus
hemopoietic cell kinase
NP_037317.2
524 aa
HCK,  G.gallus
hemopoietic cell kinase
XP_004947228.1
494 aa
hck,  X.tropicalis
hemopoietic cell kinase
NP_001015722.1
498 aa
LOC101885596,  D.rerio
tyrosine-protein kinase HCK-like
XP_005174178.1
499 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Hck is a key regulator of gene expression in alternatively activated human monocytes.
Bhattacharjee A, et al. J Biol Chem 286, 36709-23 (2011).
Multidomain assembled states of Hck tyrosine kinase in solution.
Yang S, et al. Proc Natl Acad Sci U S A 107, 15757-62 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SH2 (cl15255)
  Src homology 2 (SH2) domain.
SH3 (cl17036)
  Src Homology 3 domain superfamily.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
SH2 (cl15255)
  Src homology 2 (SH2) domain.
SH3 (cl17036)
  Src Homology 3 domain superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hck includes H.sapiens HCK and R.norvegicus Hck.

 

 

 

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