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HomoloGene:929. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

BMPR2,  H.sapiens
bone morphogenetic protein receptor, type II (serine/threonine kinase)
NP_001195.2
1038 aa
BMPR2,  P.troglodytes
bone morphogenetic protein receptor, type II (serine/threonine kinase)
XP_001172748.1
1038 aa
BMPR2,  M.mulatta
bone morphogenetic protein receptor, type II (serine/threonine kinase)
XP_001101663.1
1038 aa
BMPR2,  C.lupus
bone morphogenetic protein receptor, type II (serine/threonine kinase)
XP_536035.3
1042 aa
BMPR2,  B.taurus
bone morphogenetic protein receptor, type II (serine/threonine kinase)
XP_002685538.2
1038 aa
Bmpr2,  M.musculus
bone morphogenetic protein receptor, type II (serine/threonine kinase)
NP_031587.1
1038 aa
Bmpr2,  R.norvegicus
bone morphogenetic protein receptor, type II (serine/threonine kinase)
NP_536332.1
1038 aa
BMPR2,  G.gallus
bone morphogenetic protein receptor, type II (serine/threonine kinase)
NP_001001465.1
1031 aa
bmpr2,  X.tropicalis
bone morphogenetic protein receptor, type II (serine/threonine kinase)
XP_002937761.2
1053 aa
bmpr2b,  D.rerio
bone morphogenetic protein receptor, type II b (serine/threonine kinase)
NP_001034896.1
1071 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Pulmonary hypertension, familial primary.
Pulmonary hypertension, primary, fenfluramine-associated.
Pulmonary venoocclusive disease.



Publications
Articles associated with genes and sequences of this homology group.

Genetics and genomics of pulmonary arterial hypertension.
Soubrier F, et al. J Am Coll Cardiol 62, D13-21 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Pkinase (pfam00069)
  Protein kinase domain.
Activin_recp (pfam01064)
  Activin types I and II receptor domain.
Pkinase (pfam00069)
  Protein kinase domain.
Activin_recp (pfam01064)
  Activin types I and II receptor domain.
UNC119_bdg (pfam15435)
  UNC119-binding protein C5orf30 homologue.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Bmpr2 includes H.sapiens BMPR2 and R.norvegicus Bmpr2.

 

 

 

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