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Parasomnia

MedGen UID:
10582
Concept ID:
C0030508
Disease or Syndrome
Synonym: Parasomnias
SNOMED CT: Parasomnia (sleep disorder) (58690002); Parasomnia (58690002)
 
HPO: HP:0025234

Definition

An undesirable physical event or experience that occurs during the process of falling asleep, while asleep, or when waking up from sleep. [from HPO]

Conditions with this feature

Char syndrome
MedGen UID:
358356
Concept ID:
C1868570
Disease or Syndrome
Char syndrome is characterized by the triad of typical facial features, patent ductus arteriosus, and aplasia or hypoplasia of the middle phalanges of the fifth fingers. Typical facial features are depressed nasal bridge and broad flat nasal tip, widely spaced eyes, downslanted palpebral fissures, mild ptosis, short philtrum with prominent philtral ridges with an upward pointing vermilion border resulting in a triangular mouth, and thickened (patulous) everted lips. Less common findings include other types of congenital heart defects, other hand and foot anomalies, hypodontia, hearing loss, myopia and/or strabismus, polythelia, parasomnia, craniosynostosis (involving either the metopic or sagittal suture), and short stature.

Professional guidelines

PubMed

Howell M, Avidan AY, Foldvary-Schaefer N, Malkani RG, During EH, Roland JP, McCarter SJ, Zak RS, Carandang G, Kazmi U, Ramar K
J Clin Sleep Med 2023 Apr 1;19(4):759-768. doi: 10.5664/jcsm.10424. PMID: 36515157Free PMC Article
Zuzuárregui JRP, During EH
Neurotherapeutics 2020 Oct;17(4):1480-1494. Epub 2020 Oct 7 doi: 10.1007/s13311-020-00938-y. PMID: 33029723Free PMC Article
Drakatos P, Leschziner G
Curr Opin Pulm Med 2019 Nov;25(6):629-635. doi: 10.1097/MCP.0000000000000619. PMID: 31408014

Recent clinical studies

Etiology

Zuzuárregui JRP, During EH
Neurotherapeutics 2020 Oct;17(4):1480-1494. Epub 2020 Oct 7 doi: 10.1007/s13311-020-00938-y. PMID: 33029723Free PMC Article
Dauvilliers Y, Schenck CH, Postuma RB, Iranzo A, Luppi PH, Plazzi G, Montplaisir J, Boeve B
Nat Rev Dis Primers 2018 Aug 30;4(1):19. doi: 10.1038/s41572-018-0016-5. PMID: 30166532
Denis D, French CC, Gregory AM
Sleep Med Rev 2018 Apr;38:141-157. Epub 2017 Jun 8 doi: 10.1016/j.smrv.2017.05.005. PMID: 28735779
Gaig C, Graus F, Compta Y, Högl B, Bataller L, Brüggemann N, Giordana C, Heidbreder A, Kotschet K, Lewerenz J, Macher S, Martí MJ, Montojo T, Pérez-Pérez J, Puertas I, Seitz C, Simabukuro M, Téllez N, Wandinger KP, Iranzo A, Ercilla G, Sabater L, Santamaría J, Dalmau J
Neurology 2017 May 2;88(18):1736-1743. Epub 2017 Apr 5 doi: 10.1212/WNL.0000000000003887. PMID: 28381508Free PMC Article
Klasser GD, Rei N, Lavigne GJ
J Can Dent Assoc 2015;81:f2. PMID: 25633110

Diagnosis

Szûcs A, Mutti C, Papp A, Halász P, Parrino L
Ideggyogy Sz 2022 May 30;75(5-06):171-182. doi: 10.18071/isz.75.0171. PMID: 35819343
Stefani A, Högl B
Neurotherapeutics 2021 Jan;18(1):100-106. Epub 2020 Nov 23 doi: 10.1007/s13311-020-00966-8. PMID: 33230689Free PMC Article
Stefani A, Högl B
Neuropsychopharmacology 2020 Jan;45(1):121-128. Epub 2019 Jun 24 doi: 10.1038/s41386-019-0448-y. PMID: 31234200Free PMC Article
K Pavlova M, Latreille V
Am J Med 2019 Mar;132(3):292-299. Epub 2018 Oct 4 doi: 10.1016/j.amjmed.2018.09.021. PMID: 30292731
Dauvilliers Y, Schenck CH, Postuma RB, Iranzo A, Luppi PH, Plazzi G, Montplaisir J, Boeve B
Nat Rev Dis Primers 2018 Aug 30;4(1):19. doi: 10.1038/s41572-018-0016-5. PMID: 30166532

Therapy

Howell M, Avidan AY, Foldvary-Schaefer N, Malkani RG, During EH, Roland JP, McCarter SJ, Zak RS, Carandang G, Kazmi U, Ramar K
J Clin Sleep Med 2023 Apr 1;19(4):759-768. doi: 10.5664/jcsm.10424. PMID: 36515157Free PMC Article
Kaul M, Zee PC, Sahni AS
Neurotherapeutics 2021 Jan;18(1):217-227. Epub 2021 Feb 12 doi: 10.1007/s13311-021-01013-w. PMID: 33580483Free PMC Article
Zuzuárregui JRP, During EH
Neurotherapeutics 2020 Oct;17(4):1480-1494. Epub 2020 Oct 7 doi: 10.1007/s13311-020-00938-y. PMID: 33029723Free PMC Article
K Pavlova M, Latreille V
Am J Med 2019 Mar;132(3):292-299. Epub 2018 Oct 4 doi: 10.1016/j.amjmed.2018.09.021. PMID: 30292731
Dauvilliers Y, Schenck CH, Postuma RB, Iranzo A, Luppi PH, Plazzi G, Montplaisir J, Boeve B
Nat Rev Dis Primers 2018 Aug 30;4(1):19. doi: 10.1038/s41572-018-0016-5. PMID: 30166532

Prognosis

Howell M, Avidan AY, Foldvary-Schaefer N, Malkani RG, During EH, Roland JP, McCarter SJ, Zak RS, Carandang G, Kazmi U, Ramar K
J Clin Sleep Med 2023 Apr 1;19(4):759-768. doi: 10.5664/jcsm.10424. PMID: 36515157Free PMC Article
Scarpelli S, Alfonsi V, Gorgoni M, De Gennaro L
J Sleep Res 2022 Aug;31(4):e13609. Epub 2022 Apr 13 doi: 10.1111/jsr.13609. PMID: 35417930Free PMC Article
Antelmi E, Lippolis M, Biscarini F, Tinazzi M, Plazzi G
Sleep Med Rev 2021 Dec;60:101515. Epub 2021 Jun 10 doi: 10.1016/j.smrv.2021.101515. PMID: 34186416
Eichelberger H, Nelson ALA
Curr Probl Pediatr Adolesc Health Care 2020 Dec;50(12):100893. Epub 2020 Nov 1 doi: 10.1016/j.cppeds.2020.100893. PMID: 33139210
Moldofsky H, Gilbert R, Lue FA, MacLean AW
Sleep 1995 Nov;18(9):731-9. doi: 10.1093/sleep/18.9.731. PMID: 8638065

Clinical prediction guides

Feuerstein JS, Amara A
Curr Neurol Neurosci Rep 2023 Nov;23(11):727-734. Epub 2023 Oct 13 doi: 10.1007/s11910-023-01310-1. PMID: 37831394
During EH, Hernandez B, Miglis MG, Sum-Ping O, Hekmat A, Cahuas A, Ekelmans A, Yoshino F, Mignot E, Kushida CA
Sleep 2023 Aug 14;46(8) doi: 10.1093/sleep/zsad103. PMID: 37052688Free PMC Article
Wong LC, Huang CH, Chou WY, Hsu CJ, Tsai WC, Lee WT
Autism Res 2023 May;16(5):953-966. Epub 2023 Mar 21 doi: 10.1002/aur.2916. PMID: 36942618
Augustine A
J Clin Neurophysiol 2023 Mar 1;40(3):224-229. Epub 2022 Sep 20 doi: 10.1097/WNP.0000000000000945. PMID: 36872501
Trajanovic NN, Shapiro CM, Milovanovic S
Can J Neurol Sci 2013 Jul;40(4):536-9. doi: 10.1017/s0317167100014621. PMID: 23786736

Recent systematic reviews

Vanderkam P, Pomes C, Dzeraviashka P, Castera P, Jaafari N, Lafay-Chebassier C
CNS Spectr 2024 Apr;29(2):96-108. Epub 2024 Mar 4 doi: 10.1017/S1092852924000087. PMID: 38433577
Mundt JM, Schuiling MD, Warlick C, Dietch JR, Wescott AB, Hagenaars M, Furst A, Khorramdel K, Baron KG
Sleep Med 2023 Nov;111:36-53. Epub 2023 Sep 6 doi: 10.1016/j.sleep.2023.09.004. PMID: 37716336Free PMC Article
Li X, Zong Q, Liu L, Liu Y, Shen Y, Tang X, Wing YK, Li SX, Zhou J
Sleep Med Rev 2023 Oct;71:101810. Epub 2023 Jun 26 doi: 10.1016/j.smrv.2023.101810. PMID: 37422999
McCleery J, Sharpley AL
Cochrane Database Syst Rev 2020 Nov 15;11(11):CD009178. doi: 10.1002/14651858.CD009178.pub4. PMID: 33189083Free PMC Article
Denis D, French CC, Gregory AM
Sleep Med Rev 2018 Apr;38:141-157. Epub 2017 Jun 8 doi: 10.1016/j.smrv.2017.05.005. PMID: 28735779

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