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Infantile Hemangioma

MedGen UID:
1380698
Concept ID:
C4317089
Neoplastic Process
Synonyms: Cellular Hemangioma; Infantile Hemangioendothelioma; Juvenile Capillary Hemangioma; Juvenile Hemangioma; Strawberry Nevus

Definition

A capillary hemangioma that may regress spontaneously. It occurs in infants and children. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfantile Hemangioma

Professional guidelines

PubMed

Ziad K, Badi J, Roaa Z, Emily AH
J Cosmet Dermatol 2023 Jun;22 Suppl 2:1-7. Epub 2023 Feb 12 doi: 10.1111/jocd.15671. PMID: 36774645
Sebaratnam DF, Rodríguez Bandera AL, Wong LF, Wargon O
J Am Acad Dermatol 2021 Dec;85(6):1395-1404. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.020. PMID: 34419523
Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, Blei F, Burrows PE, Chamlin SL, Chun RH, Hess CP, Joachim S, Johnson K, Kim W, Liang MG, Maheshwari M, McCoy GN, Metry DW, Monrad PA, Pope E, Powell J, Shwayder TA, Siegel DH, Tollefson MM, Vadivelu S, Lew SM, Frieden IJ, Drolet BA
J Pediatr 2016 Nov;178:24-33.e2. Epub 2016 Sep 19 doi: 10.1016/j.jpeds.2016.07.054. PMID: 27659028Free PMC Article

Recent clinical studies

Etiology

Pope E, Lara-Corrales I, Sibbald C, Liy-Wong C, Kanigsberg N, Drolet B, Ma J
JAMA Pediatr 2022 Jan 1;176(1):34-41. doi: 10.1001/jamapediatrics.2021.4565. PMID: 34747977Free PMC Article
Sebaratnam DF, Rodríguez Bandera AL, Wong LF, Wargon O
J Am Acad Dermatol 2021 Dec;85(6):1395-1404. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.020. PMID: 34419523
Muñoz-Garza FZ, Ríos M, Roé-Crespo E, Bernabeu-Wittel J, Montserrat-García MT, Puig L, Gich I, Baselga E
JAMA Dermatol 2021 May 1;157(5):583-587. doi: 10.1001/jamadermatol.2021.0596. PMID: 33825828Free PMC Article
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(1):55-69. doi: 10.2174/1573396316666200508100038. PMID: 32384034
Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, Blei F, Burrows PE, Chamlin SL, Chun RH, Hess CP, Joachim S, Johnson K, Kim W, Liang MG, Maheshwari M, McCoy GN, Metry DW, Monrad PA, Pope E, Powell J, Shwayder TA, Siegel DH, Tollefson MM, Vadivelu S, Lew SM, Frieden IJ, Drolet BA
J Pediatr 2016 Nov;178:24-33.e2. Epub 2016 Sep 19 doi: 10.1016/j.jpeds.2016.07.054. PMID: 27659028Free PMC Article

Diagnosis

Rodríguez Bandera AI, Sebaratnam DF, Wargon O, Wong LF
J Am Acad Dermatol 2021 Dec;85(6):1379-1392. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.019. PMID: 34419524
Sebaratnam DF, Rodríguez Bandera AL, Wong LF, Wargon O
J Am Acad Dermatol 2021 Dec;85(6):1395-1404. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.020. PMID: 34419523
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(1):55-69. doi: 10.2174/1573396316666200508100038. PMID: 32384034
Iacobas I, Phung TL, Adams DM, Trenor CC 3rd, Blei F, Fishman DS, Hammill A, Masand PM, Fishman SJ
J Pediatr 2018 Dec;203:294-300.e2. Epub 2018 Sep 21 doi: 10.1016/j.jpeds.2018.08.012. PMID: 30244993
Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, Blei F, Burrows PE, Chamlin SL, Chun RH, Hess CP, Joachim S, Johnson K, Kim W, Liang MG, Maheshwari M, McCoy GN, Metry DW, Monrad PA, Pope E, Powell J, Shwayder TA, Siegel DH, Tollefson MM, Vadivelu S, Lew SM, Frieden IJ, Drolet BA
J Pediatr 2016 Nov;178:24-33.e2. Epub 2016 Sep 19 doi: 10.1016/j.jpeds.2016.07.054. PMID: 27659028Free PMC Article

Therapy

Hasbani DJ, Hamie L
Dermatol Clin 2022 Oct;40(4):383-392. Epub 2022 Sep 16 doi: 10.1016/j.det.2022.06.004. PMID: 36243426
Pope E, Lara-Corrales I, Sibbald C, Liy-Wong C, Kanigsberg N, Drolet B, Ma J
JAMA Pediatr 2022 Jan 1;176(1):34-41. doi: 10.1001/jamapediatrics.2021.4565. PMID: 34747977Free PMC Article
Sebaratnam DF, Rodríguez Bandera AL, Wong LF, Wargon O
J Am Acad Dermatol 2021 Dec;85(6):1395-1404. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.020. PMID: 34419523
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(1):55-69. doi: 10.2174/1573396316666200508100038. PMID: 32384034
Koh SP, Leadbitter P, Smithers F, Tan ST
Expert Rev Clin Pharmacol 2020 Aug;13(8):899-915. doi: 10.1080/17512433.2020.1788938. PMID: 32662682

Prognosis

Ziad K, Badi J, Roaa Z, Emily AH
J Cosmet Dermatol 2023 Jun;22 Suppl 2:1-7. Epub 2023 Feb 12 doi: 10.1111/jocd.15671. PMID: 36774645
Sun Y, Qiu F, Hu C, Guo Y, Lei S
Ann Plast Surg 2022 Feb 1;88(2):244-249. doi: 10.1097/SAP.0000000000002835. PMID: 35023872
Pahl KS, McLean TW
J Pediatr Hematol Oncol 2022 Mar 1;44(2):31-39. doi: 10.1097/MPH.0000000000002384. PMID: 34966091
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(1):55-69. doi: 10.2174/1573396316666200508100038. PMID: 32384034
Iacobas I, Phung TL, Adams DM, Trenor CC 3rd, Blei F, Fishman DS, Hammill A, Masand PM, Fishman SJ
J Pediatr 2018 Dec;203:294-300.e2. Epub 2018 Sep 21 doi: 10.1016/j.jpeds.2018.08.012. PMID: 30244993

Clinical prediction guides

Colmant C, Powell J
Paediatr Drugs 2022 Jan;24(1):29-43. Epub 2021 Oct 22 doi: 10.1007/s40272-021-00477-9. PMID: 34677814
Muñoz-Garza FZ, Ríos M, Roé-Crespo E, Bernabeu-Wittel J, Montserrat-García MT, Puig L, Gich I, Baselga E
JAMA Dermatol 2021 May 1;157(5):583-587. doi: 10.1001/jamadermatol.2021.0596. PMID: 33825828Free PMC Article
Leung AKC, Lam JM, Leong KF, Hon KL
Curr Pediatr Rev 2021;17(1):55-69. doi: 10.2174/1573396316666200508100038. PMID: 32384034
Hochman M
Facial Plast Surg Clin North Am 2014 Nov;22(4):509-21. Epub 2014 Aug 21 doi: 10.1016/j.fsc.2014.07.003. PMID: 25444725
Kwon EK, Seefeldt M, Drolet BA
Am J Clin Dermatol 2013 Apr;14(2):111-23. doi: 10.1007/s40257-013-0008-x. PMID: 23338947

Recent systematic reviews

Li W, Kang J, Bai S, Yuan L, Liu J, Bi Y, Sun J, He Y
Eur J Pediatr 2023 Feb;182(2):479-488. Epub 2022 Nov 24 doi: 10.1007/s00431-022-04688-1. PMID: 36434402
Kleinman EP, Blei F, Adams D, Greenberger S
Pediatr Res 2023 May;93(6):1470-1479. Epub 2022 Sep 30 doi: 10.1038/s41390-022-02325-z. PMID: 36180586
Chen T, Gudipudi R, Nguyen SA, Carroll W, Clemmens C
Ann Otol Rhinol Laryngol 2023 Mar;132(3):332-340. Epub 2022 Apr 25 doi: 10.1177/00034894221089758. PMID: 35466712
Lee JC, Modiri O, England RW, Shawber CJ, Wu JK
Plast Reconstr Surg 2021 Apr 1;147(4):875-885. doi: 10.1097/PRS.0000000000007699. PMID: 33776033
Chinnadurai S, Sathe NA, Surawicz T
Lasers Surg Med 2016 Mar;48(3):221-33. Epub 2015 Dec 29 doi: 10.1002/lsm.22455. PMID: 26711436

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