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Middle cerebral artery infarction

MedGen UID:
152845
Concept ID:
C0740392
Disease or Syndrome
Synonyms: Cerebral Infarction, Middle Cerebral Artery; Infarct, MCA; Infarction, Middle Cerebral Artery; Infarcts, MCA; MCA Infarct; MCA Infarction; MCA Infarcts; Middle Cerebral Artery Circulation Infarction; Middle Cerebral Artery Infarction; Middle Cerebral Artery Stroke; Stroke, Middle Cerebral Artery
 
HPO: HP:0033762
Monarch Initiative: MONDO:0006857

Definition

Necrosis occurring in the middle cerebral artery distribution system which brings blood to the entire lateral aspects of each cerebral hemisphere. Clinical signs include impaired cognition; aphasia; agraphia; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMiddle cerebral artery infarction

Recent clinical studies

Etiology

Yi X, Zhou Q, Qing T, Ming B, Lin J, Li J, Lin J
BMC Neurol 2021 Nov 9;21(1):437. doi: 10.1186/s12883-021-02456-6. PMID: 34753429Free PMC Article
Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A
J Stroke Cerebrovasc Dis 2021 May;30(5):105717. Epub 2021 Mar 6 doi: 10.1016/j.jstrokecerebrovasdis.2021.105717. PMID: 33690027
Yuan R, Wu S, Cheng Y, Ye K, Hao Z, Zhang S, Liu Y, Liu M
Curr Neurovasc Res 2020;17(2):131-139. doi: 10.2174/1567202617666200207125552. PMID: 32031070
Kilic M, Ertem DH, Ozdemir B
Medicina (Kaunas) 2019 Jan 30;55(2) doi: 10.3390/medicina55020031. PMID: 30704138Free PMC Article
Lammy S, Fivey P, Sangra M
J Med Case Rep 2016 Dec 20;10(1):368. doi: 10.1186/s13256-016-1145-7. PMID: 27998316Free PMC Article

Diagnosis

Yi X, Zhou Q, Qing T, Ming B, Lin J, Li J, Lin J
BMC Neurol 2021 Nov 9;21(1):437. doi: 10.1186/s12883-021-02456-6. PMID: 34753429Free PMC Article
Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A
J Stroke Cerebrovasc Dis 2021 May;30(5):105717. Epub 2021 Mar 6 doi: 10.1016/j.jstrokecerebrovasdis.2021.105717. PMID: 33690027
Kilic M, Ertem DH, Ozdemir B
Medicina (Kaunas) 2019 Jan 30;55(2) doi: 10.3390/medicina55020031. PMID: 30704138Free PMC Article
Sundseth J, Sundseth A, Jacobsen EA, Pripp AH, Sorteberg W, Altmann M, Lindegaard KF, Berg-Johnsen J, Thommessen B
Acta Neurochir (Wien) 2017 Feb;159(2):301-306. Epub 2016 Dec 10 doi: 10.1007/s00701-016-3049-0. PMID: 27942881
Lammy S, Fivey P, Sangra M
J Med Case Rep 2016 Dec 20;10(1):368. doi: 10.1186/s13256-016-1145-7. PMID: 27998316Free PMC Article

Therapy

Wei H, Jia FM, Yin HX, Guo ZL
Biosci Rep 2020 Jan 31;40(1) doi: 10.1042/BSR20191448. PMID: 31854446Free PMC Article
Das S, Mitchell P, Ross N, Whitfield PC
World Neurosurg 2019 Mar;123:8-16. Epub 2018 Nov 27 doi: 10.1016/j.wneu.2018.11.176. PMID: 30500591
Finger T, Prinz V, Schreck E, Pinczolits A, Bayerl S, Liman T, Woitzik J, Vajkoczy P
Clin Neurol Neurosurg 2017 Feb;153:27-34. Epub 2016 Dec 9 doi: 10.1016/j.clineuro.2016.12.001. PMID: 28012353
Sundseth J, Sundseth A, Jacobsen EA, Pripp AH, Sorteberg W, Altmann M, Lindegaard KF, Berg-Johnsen J, Thommessen B
Acta Neurochir (Wien) 2017 Feb;159(2):301-306. Epub 2016 Dec 10 doi: 10.1007/s00701-016-3049-0. PMID: 27942881
Arboix A, García-Eroles L, Oliveres M, Comes E, Sánchez MJ, Massons J
Rev Invest Clin 2015 Jan-Feb;67(1):64-70. PMID: 25857586

Prognosis

Yi X, Zhou Q, Qing T, Ming B, Lin J, Li J, Lin J
BMC Neurol 2021 Nov 9;21(1):437. doi: 10.1186/s12883-021-02456-6. PMID: 34753429Free PMC Article
Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A
J Stroke Cerebrovasc Dis 2021 May;30(5):105717. Epub 2021 Mar 6 doi: 10.1016/j.jstrokecerebrovasdis.2021.105717. PMID: 33690027
Kilic M, Ertem DH, Ozdemir B
Medicina (Kaunas) 2019 Jan 30;55(2) doi: 10.3390/medicina55020031. PMID: 30704138Free PMC Article
Sundseth J, Sundseth A, Jacobsen EA, Pripp AH, Sorteberg W, Altmann M, Lindegaard KF, Berg-Johnsen J, Thommessen B
Acta Neurochir (Wien) 2017 Feb;159(2):301-306. Epub 2016 Dec 10 doi: 10.1007/s00701-016-3049-0. PMID: 27942881
Lammy S, Fivey P, Sangra M
J Med Case Rep 2016 Dec 20;10(1):368. doi: 10.1186/s13256-016-1145-7. PMID: 27998316Free PMC Article

Clinical prediction guides

Yi X, Zhou Q, Qing T, Ming B, Lin J, Li J, Lin J
BMC Neurol 2021 Nov 9;21(1):437. doi: 10.1186/s12883-021-02456-6. PMID: 34753429Free PMC Article
Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Villacampa-Jiménez JJ, Jiménez A
J Stroke Cerebrovasc Dis 2021 May;30(5):105717. Epub 2021 Mar 6 doi: 10.1016/j.jstrokecerebrovasdis.2021.105717. PMID: 33690027
Kilic M, Ertem DH, Ozdemir B
Medicina (Kaunas) 2019 Jan 30;55(2) doi: 10.3390/medicina55020031. PMID: 30704138Free PMC Article
Sundseth J, Sundseth A, Jacobsen EA, Pripp AH, Sorteberg W, Altmann M, Lindegaard KF, Berg-Johnsen J, Thommessen B
Acta Neurochir (Wien) 2017 Feb;159(2):301-306. Epub 2016 Dec 10 doi: 10.1007/s00701-016-3049-0. PMID: 27942881
Lammy S, Fivey P, Sangra M
J Med Case Rep 2016 Dec 20;10(1):368. doi: 10.1186/s13256-016-1145-7. PMID: 27998316Free PMC Article

Recent systematic reviews

Goedemans T, Verbaan D, Coert BA, Kerklaan B, van den Berg R, Coutinho JM, van Middelaar T, Nederkoorn PJ, Vandertop WP, van den Munckhof P
Neurosurgery 2020 Mar 1;86(3):E318-E325. doi: 10.1093/neuros/nyz522. PMID: 31943069Free PMC Article
Wei H, Jia FM, Yin HX, Guo ZL
Biosci Rep 2020 Jan 31;40(1) doi: 10.1042/BSR20191448. PMID: 31854446Free PMC Article
Chen Z, Zhang X, Liu C
Clin Neurol Neurosurg 2020 Jan;188:105569. Epub 2019 Oct 23 doi: 10.1016/j.clineuro.2019.105569. PMID: 31710882
Das S, Mitchell P, Ross N, Whitfield PC
World Neurosurg 2019 Mar;123:8-16. Epub 2018 Nov 27 doi: 10.1016/j.wneu.2018.11.176. PMID: 30500591
Gul W, Fuller HR, Wright H, Sen J
World Neurosurg 2018 Dec;120:e902-e920. Epub 2018 Sep 5 doi: 10.1016/j.wneu.2018.08.189. PMID: 30193963

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